Α-BUNGAROTOXIN

作品数：3被引量：5H指数：1
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相关领域：医药卫生更多>>
相关作者：钱友存范春阳龚毅杨胜利更多>>
相关机构：中国科学院南京师范大学更多>>
相关期刊：《Bioactive Materials》《Zoological Research》《Chinese Chemical Letters》更多>>
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A genetically engineered neuronal membrane-based nanotoxoid elicits protective immunity against neurotoxins
《Bioactive Materials》2024年第8期321-330,共10页Zhongyuan Guo Audrey T.Zhu Xiaoli Wei Yao Jiang Yiyan Yu Ilkoo Noh Weiwei Gao Ronnie H.Fang Liangfang Zhang 
supported by the Defense Threat Reduction Agency Joint Science and Technology Office for Chemical and Biological Defense under award number HDTRA1-21-1-0010;the National Institutes of Health under Award Numbers R21AI159492 and R21AI175904.
Given their dangerous effects on the nervous system,neurotoxins represent a significant threat to public health.Various therapeutic approaches,including chelating agents,receptor decoys,and toxin-neutralizing antibodi...
关键词：Antivirulence vaccine Cell membrane-coated nanoparticle Genetic engineering Α-BUNGAROTOXIN Nanotoxoid 
Total synthesis of snake toxin α-bungarotoxin and its analogues by hydrazide-based native chemical ligation被引量：1
《Chinese Chemical Letters》2018年第7期1139-1142,共4页Xiao-Qi Guo Jun Liang Ying Li Yong Zhang Dongliang Huang Changlin Tian 
supported by the Science and Technological Fund of Anhui Province for Outstanding Youth(No. 1808085J04);the Innovative Program Development Foundation Hefei Center Physical Science Technology(No. 2017FXCX002)
Nicotinic acetylcholine receptors(nAChRs) play important roles in intercellular communications of nerve cells. α-Bungarotoxins(αBtx) is a moderator for the nAChRs. Chemical synthesis provides a promising way to acce...
关键词：Chemical synthesis Native chemical ligation Peptide hydrazide Α-BUNGAROTOXIN Nicotinic acetylcholine receptors 
MOLECULAR CLONING AND FUNCTIONAL EXPRESSION OF α-BUNGAROTOXIN (V31) FROM CHINESE CONTINENTAL BANDED KRAIT被引量：4
《Zoological Research》2000年第1期41-47,共7页钱友存 范春阳 胡太山 杨运桂 杨胜利 龚毅 
the"95"great program of Chinese Academy of Sciences! (KY95 1-A1-3 0 1-0 2 )
The cDNA encoding a variant of α bungarotoxin was cloned from the venom glands of Bungarus multicinctus by RT PCR.The deduced protein precursor contained a 21 amino acid signal peptide and a following 74 amino ...
关键词：bungarotoxin (V31) cDNA cloning Fusion expression In vivo   toxicity 
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