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supported by the Basic Science Center Program of National Natural Science Foundation of China(No.T2288102);the Key Program of the National Natural Science Foundation of China(No.32230059);the National Natural Science Foundation of China(No.32101086);the National Postdoctoral Program for Innovative Talents(BX2021101);the China Postdoctoral Science Foundation Funded Project(2021M701192);Fundamental Research Funds for the Central Universities(JKD01221507);the Foundation of Frontiers Science Center for Materiobiology and Dynamic Chemistry(JKVD1211002).
Recombinant human bone morphogenetic protein-2(rhBMP-2)is the predominant growth factor that effectively induces osteogenic differentiation in orthopedic procedures.However,the bioactivity and stability of rhBMP-2 are...