PIPERIDONE

作品数：7被引量：1H指数：1
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Synthesis and Thermotropic of PAMEs Based on 1-Phenethyl-4- Piperidone Moiety
《Research and Application of Materials Science》2020年第2期51-57,共7页Ismail A.Alkskas AMNA AAbayo 
The experiments were conducted by Amna A.Abayo and writing,paper discussion and revision was contributed by Ismail A.Alkskas,who was the corresponding author.
New poly(azomethine-ether)s PAMEs containing 1-phenethyl-4-piperidone moiety have been synthesized through a solution polymerization of various diformyl-a,w-diphenoxyalkanes,I-IV with 3,5-bis(p-aminobenzylidene)-1-Phe...
关键词：PAMEs PIPERIDONE THERMOTROPIC Texture observation 
3,5-Bis(arylidene)-4-piperidones as potential dengue protease inhibitors
《Acta Pharmaceutica Sinica B》2017年第4期479-484,共6页Hasnah Osman Nor Hashima Idris Ezatul Ezleen Kamarulzaman Habibah A.Wahab Mohd.Zaheen Hassan 
The Research University Team Grant (RUT/1001/PKIMIA/855006) provided by Universiti Sains Malaysia(USM)
Dengue is a severe mosquito-borne viral infection causing half a million deaths annually. Dengue virus NS2B/NS3 protease is a validated target for anti-dengue drug design. A series of hitherto unreported 3,5-bis(aryli...
关键词：Dengue virus NS2B/NS3 protease PIPERIDONE α β-Unsaturated ketone Protease inhibitors 
Synthesis and anticancer activity containing benzyl piperidone study of curcumin-related compounds
《Journal of Chinese Pharmaceutical Sciences》2015年第8期524-529,共6页Daiying Zhou Suqing Zhao Xi Zheng Zhiyun Du Kun Zhang 
China National Science Foundation Grants （Grant No. 21272043）, The PhD Start-up Fund of Natural Science Foundation of Guangdong Province （Grant No. 2014A030310329） and by Medical Scientific Research Foundation of Guangdong Province （Grant No. B2014072）.
Sixteen curcumin-related compounds containing benzyl piperidone were synthesized and evaluated for their anticancer activity by the MTT assay towards cultured prostate cancer （PC-3）, pancreatic cancer （BxPC-3）, co...
关键词：Curcumin-related compounds SYNTHESIS Anticancer activity 
A novel and concise synthetic access to chiral 2-substituted-4-piperidone
《Science China Chemistry》2014年第7期945-953,共9页CHEN BaiLing WANG Bing LIN GuoQiang 
CAS Key Laboratory of Synthetic Chemistry of Natural Substances (2008DP173071) for analysis support
A novel and concise synthetic access to enantiopure chiral 2-aryl/alkyl substituted 4-piperidone has been demonstrated.This new route features two key steps:the highly diastereoselective conjugate addition of homochir...
关键词：chiral 2-substituted-4-piperidone homochiral lithium amide diastereoselective conjugate addition lithium-iodine ex-change intramolecular carbonyl formation 
Cross double Mannich reaction catalyzed by I_2:Synthesis of highly substituted 4-piperidones
《Chinese Chemical Letters》2012年第3期309-312,共4页Xiao Dong Jia Xiang Ning Chen Cong De Huo Fang Fang Peng Chang Qing Xi Cun Wang 
NSFC(No21002079)and Project(No20096203120002);supported by the Ministry of Education of the People's Republic of China;Technological Innovation Project(NosNWNU-KJCXGC-03-75 and NWNU-KJCXGC-03-64) of Northwest Normal University for supporting our research
Cross double Mannich reaction and tandem cyclization were achieved under iodine catalyzed conditions,yielding a series of highly substituted 4-piperidones.Among the possible diastereomers,only one diastereomer was iso...
关键词：Mannich reaction 4-Piperidone Tandem cyclization IODINE 
N-（Substituted benzyl）-3,5-bis（benzylidene）-4-piperidones： Synthesis and Preliminary Anti-leukemia Activity （I）被引量：1
《Chinese Journal of Chemistry》2011年第10期2109-2113,共5页王静 孟雯 倪振杰 薛思佳 
A series of novel N-（substituted benzyl）-3,5-bis（benzylidene）-4-piperidones 5a--50 were synthesized with substituted benzylamines as raw materials via a series of Michael addition, Dieckmann condensation, hydrolys...
关键词：4-piperidone SYNTHESIS inhibition leukemia K562 cell MTT 
Syntheses of 3－Methyl－1－propyl－4－piperidoneand1－Methyl－3，7－dipropyl－3，7－diazabicyclo［3，3，1］nonan－9－one
《Chemical Research in Chinese Universities》1994年第3期266-271,共6页WANG Yu-huan , WANG Guo-jia, ZHANG Wei-ge, DU BO, FANG BO-yanYU Gui and CHENG Yue-mei(Department of Chemistry, Jilin University, Changchun, 130023) 
Ｓｙｎｔｈｅｓｅｓｏｆ３－Ｍｅｔｈｙｌ－１－ｐｒｏｐｙｌ－４－ｐｉｐｅｒｉｄｏｎｅａｎｄ１－Ｍｅｔｈｙｌ－３，７－ｄｉｐｒｏｐｙｌ－３，７－ｄｉａｚａｂｉｃｙｃｌｏ［３，３，１］ｎｏｎａｎ－９－ｏｎｅＷＡＮＧＹｕ－ｈ...
关键词：Methyl- 1-propyl-4-piperidone 1-Methyl-3 7-dipropyl-3 7-diazabi-cyclo[3 3 1]nonan-9-one Synthesis Catalysis 
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