We thank the Qingdao Marine Science and Technology Center(No.2022QNLM030003-2);the Fundamental Research Funds for the Central Universities,Taishan Scholar Program of Shandong Province(No.tsqn201909056);National Natural Science Foundation of China(No.22171251)for financial support.
An efficient asymmetric[4+2]cyclization of hydroxyphenyl indolinone with azlactone for the synthesis of spirooxindoleδ-lactone has been developed,which realized the first asymmetric reaction of hydroxyphenyl indolino...
The macrophage migration inhibitory factor has been implicated in a number ofimmune and inflammatory processes. MIF presents particular opportunities for drug design anddevelopment with potential therapeutic applicati...