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CREATINASE: 作品数：1被引量：0H指数：0; 导出分析报告; 相关期刊：《mLife》更多>>; 相关基金：国家自然科学基金更多>>

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Optimizing enzyme thermostability by combining multiple mutations using protein language model: 《mLife》2024年第4期492-504,共13页Jiahao Bian Pan Tan Ting Nie Liang Hong Guang‐Yu Yang; supported by the Key‐Area Research and Development Program of Guangdong Province,China(2022B1111050001);the National Natural Science Foundation of China(Grant Nos.32030063 and 32371483);the Shanghai Pilot Program for Basic Research‐Shanghai Jiao Tong University.; Optimizing enzyme thermostability is essential for advancements in protein science and industrial applications.Currently,(semi‐)rational design and random mutagenesis methods can accurately identify single‐point mut...; 关键词：combinatorial mutants CREATINASE EPISTASIS protein language model thermostability