supported in part by grants from the National Key Research and Development Program of China(2022YFC2303100 for L.P and W.L);the National Natural Science Foundation of China(32030002 and 22193070 for W.L);the Science and Technology Commission of Shanghai Municipality(20XD1425200 for L.P);the CAS Youth Interdisciplinary Team(JCTD-2022-10 for L.P).
Dehydration of serine/threonine residues necessitates the activity of a dehydratase enzyme(domain)during the biosynthesis of RiPP.Recently,it was reported that dehydration in the thioviridamide pathway relies on a dis...