Aim To develop an HPLC method with fluorescence detection for the assay ofDL111-IT in rabbit plasma. Methods DL111-IT and internal standard glybenzcyclamide in rabbit plasmawere extracted with chloroform. The determin...
Project supported by the Province Natural Foundation of Zhejiang; No598155.
AIM: To study the effects of diphenytriazol on cytochrome P-450 (CYP)enzymes. METHODS: SD rats were pretreated with diphenytriazol. The catalytic activities of rat livermicrosomes were determined by assaying ethoxyres...