Third generation of quinolones,such as levofloxacin and moxifloxacin,-containing regimens are often used in second-line or rescue treatment of Helicobacter pylori infection.However,the increasing antibiotic resistance...
Project supported by the National Natural Science Foundation of China(No.21272086)
A new compound [C19H19N3O3F2Cl·C4H3O4·H2O](I),(7-((7S)-7-aminospiro[2.4]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid fumaric acid monohydrate...
Helicobacter pylori is a highly successful bacterium with a high global prevalence and the infection carries significant disease burden. It is also becoming increasingly difficult to eradicate and the main reason for ...