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supported by grants from the National Key R&D Program of China(no.2019YFA0905700 and 2019YFA0905300);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIPKJGG-002);the Key Research Program of the Chinese Academy of Sciences(KFZD-SW-215);the Tianjin Science Fund for Distinguished Young Scholars(18JCJQJC48300);the National Science and Technology Major Project(2018ZX09711001-006-003);the Major Science and Technique Programs in Yunnan Province(2019ZF011);the National Science Fund for Excellent Young Scholars(31922047).
Diosgenin,mainly produced by Dioscorea species,is a traditional precursor of most hormonal drugs in the pharmaceutical industry.The mechanisms that underlie the origin and evolution of diosgenin biosynthesis in plants...