the support of K.C.Wong Education Foundation (China);financially supported by the National Natural Science Foundation of China (No.82071974);Shenzhen Basic Research Project (JCYJ20180503182116931, China);Guangdong Basic and Applied Basic Research Foundation (2020A1515011192, 2018A0303130052, China);Guangzhou Key Research Program on Brain Science (202007030008, China);the Fundamental Research Funds for the Central Universities (21619104, 21621051, China)
As a member of cyclic nucleotide phosphodiesterase(PDE)enzyme family,PDE10A is in charge of the degradation of cyclic adenosine(cAMP)and guanosine monophosphates(cGMP).While PDE10A is primarily expressed in the medium...