TRIPLEX

作品数:41被引量:37H指数:3
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In vitro triplex formation and functional analysis of TFOs designed against human c-sis/PDGF-B proto-oncogene
《Science China(Life Sciences)》2001年第1期83-91,共9页刘静 徐人欢 金由辛 王德宝 
the State Key Programs Basic Research of China (Grant No. G1998051103) and National High Technology Programs of China (Grant No. 863-102-08-8).
PDGF (platelet derived growth factor) has been shown to play animportant role in tumorigenesis, tumor growth, atherosclerosis and inflammation and other various pathologic settings. PDGF-B chain gene is 92% homologous...
关键词:c-sis/PDGF-B proto-oncogene  triplex-forming OLIGONUCLEOTIDES (TFO). 
Influence of loop sequence on relative stability of bimolecular triplex DNA
《Science China(Life Sciences)》1998年第4期381-386,共6页杨林静 李任植 王琛 刘峁子 苏明 白春礼 
ProjectsupportedbytheNationalNaturalScienceFoundationofChina (GrantNo .2 95 2 5 30 4 ) .
The structures of 20 bimolecular triplexes have been built and simulated by molecular mechanics. The sequence of pyrimidine strand is 5′ dTTCTTTC L\-1TTTL\-5 CTTTTCTT 3′, where the five nucleotides underlined compos...
关键词:bimolecular TRIPLEX LOOP SEQUENCE STABILITY MOLECULAR mechanics. 
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