supported by the National Natural Science Foundation of China (32170192 and 32370200 to Z.T);National Youth Talent Support Program.
Di-and tri-methylation of lysine 36 on histone H3(H3K36me2/3)is catalysed by histone methyltransferase Set2,which plays an essential role in transcriptional regulation.Although there is a single H3K36 methyltransferas...