METHYLOTROPHY

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Scanning the active center of formolase to identify key residues for enhanced C1 to C3 bioconversion
《Bioresources and Bioprocessing》2024年第1期655-661,共7页Guimin Cheng Hongbing Sun Qian Wang Jinxing Yang Jing Qiao Cheng Zhong Tao Cai Yu Wang 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDC0110201);the National Natural Science Foundation of China(32222004 and 32070083);the Major Program and Innovation Fund of Haihe Laboratory of Synthetic Biology(22HHSWSS00003 and 22HHSWSS00017);the CAS Project for Young Scientists in Basic Research(YSBR-072);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2021177);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-008).
Background Formolase(FLS)is a computationally designed enzyme that catalyzes the carboligation of two or three C1 formaldehyde molecules into C2 glycolaldehyde or C3 dihydroxyacetone(DHA).FLS lays the foundation for s...
关键词：Formolase DIHYDROXYACETONE C1 bioconversion Carbon fixation Synthetic methylotrophy 
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