METHYLOTROPHY

作品数：3被引量：4H指数：2
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Scanning the active center of formolase to identify key residues for enhanced C1 to C3 bioconversion
《Bioresources and Bioprocessing》2024年第1期655-661,共7页Guimin Cheng Hongbing Sun Qian Wang Jinxing Yang Jing Qiao Cheng Zhong Tao Cai Yu Wang 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDC0110201);the National Natural Science Foundation of China(32222004 and 32070083);the Major Program and Innovation Fund of Haihe Laboratory of Synthetic Biology(22HHSWSS00003 and 22HHSWSS00017);the CAS Project for Young Scientists in Basic Research(YSBR-072);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2021177);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-008).
Background Formolase(FLS)is a computationally designed enzyme that catalyzes the carboligation of two or three C1 formaldehyde molecules into C2 glycolaldehyde or C3 dihydroxyacetone(DHA).FLS lays the foundation for s...
关键词：Formolase DIHYDROXYACETONE C1 bioconversion Carbon fixation Synthetic methylotrophy 
Directed evolution of a neutrophilic and mesophilic methanol dehydrogenase based on high-throughput and accurate measurement of formaldehyde被引量：2
《Synthetic and Systems Biotechnology》2023年第3期386-395,共10页Jin Qian Liwen Fan Jinxing Yang Jinhui Feng Ning Gao Guimin Cheng Wei Pu Wenjuan Zhou Tao Cai Shuang Li Ping Zheng Jibin Sun Depei Wang Yu Wang 
the National Key Research and Development Program of China(2018YFA0901500);the National Natural Science Foundation of China(32070083 and 32222004);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2021177);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-008);the Innovation Fund of Haihe Laboratory of Synthetic Biology.
Methanol is a promising one-carbon feedstock for biomanufacturing,which can be sustainably produced from carbon dioxide and natural gas.However,the efficiency of methanol bioconversion is limited by the poor catalytic...
关键词：Methanol dehydrogenase Formaldehyde biosensor Directed evolution C1 bioconversion Methanol oxidation METHYLOTROPHY 
Benchmarking two Saccharomyces cerevisiae laboratory strains for growth and transcriptional response to methanol被引量：2
《Synthetic and Systems Biotechnology》2019年第4期180-188,共9页Monica I.Espinosa Thomas C.Williams Isak S.Pretorius Ian T.Paulsen 
The Synthetic Biology initiative at Macquarie University is financially supported by an internal grant from the University,and external grants from Bioplatforms Australia,the New South Wales(NSW)Chief Scientist and Engineer,and the NSW Government's Department of Primary Industries.Ian Paulsen is supported by an Australian Research Council Laureate Fellowship.TCW and MIE are supported by the CSIRO Synthetic Biology Future Science Platform and Macquarie University.
One-carbon compounds,such as methanol,are becoming potential alternatives to sugars as feedstocks for the biological production of chemicals,fuels,foods,and pharmaceuticals.Efficient biological production often requir...
关键词：YEAST METHYLOTROPHY Synthetic biology Metabolic engineering MIG3 METHANOL 
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