The authors thank the Genomics Shared Resource(GSR)core facility at the University of California,Davis Health,Dr.Clifford G Tepper,Stephanie Liu,Ryan Davis,for helping in performing spatial RNA sequencing,and William Amato for his assistance in the quantification of immunohistochemistry slides.This manuscript is supported by grants funded by the USA National Institutes of Health(NIH)T32 CA108459e15,R01CA222490,R50CA243787.BioRender was used to draw mice figures in schematic experimental design.
This study examines inhibiting galectin 1(Gal1)as a treatment option for hepatocellular carcinoma(HCC).Gal1 has immunosuppressive and cancer-promoting roles.Our data showed that Gal1 was highly expressed in human and ...
Acknowledgments We thank Dr. Ron Salzman for his critical review of this manuscript. This project was supported by the USDA National Research Initiative grant# 2005-35604-15438, by the Natural Science Foundation of Jiangsu Province (BK20130711), and by Basic Science Research Program through the NRF of Korea funded by the MOEST (2012R1A1A2044114).
Griffonia simplicifolia lectin II (GSII) and wheat germ agglutinin (WGA) are N-acetylglucosamine-binding lectins. Previous studies demonstrated that they have anti- insect activity, a property potentially useful i...