PRODRUGS

作品数：67被引量：100H指数：5
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相关领域：医药卫生化学工程更多>>
相关作者：张礼和谢璐佳郭颖卢俊峰徐靖源更多>>
相关机构：中国医学科学院北京协和医学院北京大学香港城市大学天津医科大学更多>>
相关期刊：《Nano-Micro Letters》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金天津市自然科学基金中国博士后科学基金教育部留学回国人员科研启动基金更多>>
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Recent progress in stimuli-activable metallo-prodrugs for cancer therapy
《Smart Molecules》2024年第3期14-38,共25页Jinzhe Liang Fangmian Wei Hui Chao 
supported by the National Natural Science Foundation of China(Nos.22120102002 and 92353301);the Science and Technology Innovation Program of Hunan Province of China(No.2021RC5028).
The clinical approval of platinum-based drugs has prompted the development of novel metallo-complexes during the last several decades,while severe problems,especially for poor water solubility,drug resistance and toxi...
关键词：cancer therapy metallo-prodrugs stimuli-activable 
Activatable theranostic prodrug scaffold with tunable drug release rate for sequential photodynamic and chemotherapy
《Smart Molecules》2024年第1期110-117,共8页Si-Yu Wang Ying-Hao Pan Yu-Chen Qu Xiao-Xiao Chen Na Shao Li-Ya Niu Qing-Zheng Yang 
support from the National Natural Science Foundation of China(22177014,22231001 and 21971023);the Fundamental Research Funds for the Central Universities and Key Laboratory of Photochemical Conversion and Optoelectronic Materials,TIPC,CAS.
Glutathione(GSH)-activated prodrugs are promising for overcoming the limitations of conventional anti-tumor drugs.However,current GSH-responsive disulfide groups exhibit unregulated reactivity,making it impossible to ...
关键词：combinational therapy fluorescent probes photodynamic therapy PRODRUGS theranostic agents 
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