ALDOLASE

作品数:29被引量:53H指数:4
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相关作者:何国雄蔡颖梁清华杨波杨波更多>>
相关机构:中南大学华中师范大学南京农业大学西北农林科技大学更多>>
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Improvement of the activity and thermostability of l‑threonine aldolase from Pseudomonas putida via tailoring of the active sites lining the binding pocket
《Systems Microbiology and Biomanufacturing》2023年第3期440-448,共9页Lihong Li Rongzhen Zhang Wenchi Zhang Yan Xu 
the National Key research and Development Program of China(2018YFA0900302);the National Science Foundation of China(32271487,31970045);the National Firstclass Discipline Program of Light Industry Technology and Engineering(LITE2018-12);the Program of Introducing Talents of Discipline to Universities(111-2-06);Top-notch Academic Programs Project of Jiangsu Higher Education Institutions.
l-threonine aldolases catalyze the conversion of glycine and aldehydes to synthesizeβ-hydroxy-α-amino acids with unsatisfactory enzyme activity.Here,we expressed the l-threonine aldolase from Pseudomonas putida KT24...
关键词:Threonine aldolases Pseudomonas putida Catalytic efficiency Thermostability Molecular dynamics simulations 
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