This study was supported by grants from National Natural Science Foundation of China (No. 81100264, No. 81360076, and No. 81100498), the Hubei Provincial Health Department Foundation for Young Scholars (QJX2012-04) and the Deutsche Forschungsgemeinschaft SFB621/C9 (to US).Acknowledgment: The authors thank the participants involved in this study and Dr. Ma Ruling for helping with data analysis.
Background Diarrhea is a common clinical feature of ulcerative colitis resulting from unbalanced intestinal fluid and salt absorption and secretion.The Cl-/HCO3-exchanger SLC26A3 is strongly expressed in the mid-dista...