supported by the National Institute of Dental and Craniofacial Research(DE015846);a National Research Foundation of Korea(NRF)grant funded by the Korean government(MEST)(NRF-2018R1A5A2024418 and NRF-2020R1A2C2100543)。
Oligodontia is the congenital absence of six or more teeth and comprises the more severe forms of tooth agenesis.Many genes have been implicated in the etiology of tooth agenesis,which is highly variable in its clinic...
supported by the National Natural Science Foundation of China(81970902,81771054,and 81600846).
The goal of this study was to identify MSX1 gene variants in multiple Chinese families with nonsyndromic oligodontia and analyse the functional influence of these variants.Whole-exome sequencing(WES)and Sanger sequenc...
Hypodontia is defined as the developmental absence of one or more teeth which can affect both the primary and permanent dentition. During the diagnosis procedure several other dental and oral symptoms can be observed....