This study was supported by the GePEM(Instituto de Salud Carlos III(ISCIII)/PI16/01478/Cofinanciado FEDER);DIAVIR(Instituto de Salud Carlos III(ISCIII)/DTS19/00049/Cofinanciado FEDER;Proyecto de Desarrollo Tecnológico en Salud),Resvi-Omics(Instituto de Salud Carlos III(ISCIII)/PI19/01039/Cofinanciado FEDER),BI-BACVIR(PRIS-3;Agencia de Conocimiento en Salud(ACIS)-Servicio Gallego de Salud(SERGAS)-Xunta de Galicia;Spain),Programa Traslaciona Covid-19(ACIS-Servicio Gallego de Salud(SERGAS)-Xunta de Galicia;Spain)and Axencia Galega de Innovación(GAIN;IN607B 2020/08-Xunta de Galicia;Spain)to A.S.;and ReSVinext(Instituto de Salud Carlos III(ISCIII)/PI16/01569/Cofinanciado FEDER),and Enterogen(Instituto de Salud Carlos III(ISCIII)/PI19/01090/Cofinanciado FEDER)to F.M.-T;We gratefully acknowledge GISAID and contributing laboratories(Supplementary Table S1)for giving us access to the SAR-CoV-2 genomes used in the present study.
DEAR EDITOR,Analysis of SARS-CoV-2 genome variation using a minimal number of selected informative sites conforming a genetic barcode presents several drawbacks.We show that purely mathematical procedures for site sel...