HEMOGLOBIN

作品数：387被引量：453H指数：9
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Dynamin like protein 1 participated in the hemoglobin uptake pathway of Plasmodium falciparum被引量：1
《Chinese Medical Journal》2009年第14期1686-1691,共6页ZHOU Hong-chang GAO Yu-hui ZHONG Xiang WANG Heng 
This work was supported by the research grants from the National Basic Research Program of China （973 Program, No. 2007CB513100）, the High-Tech Research and Development Program of China （863 Program, No. 2006AA028471）, the China＇s Major Infectious Diseases of Major Special Program （No. 2008ZX10004-011）, and the grant of National Natural Science Foundation of China （No. 30170876）.
Background During the blood stage of malaria infection, parasites internalize in the host red blood cells and degrade massive amounts of hemoglobin for their development. Although the morphology of the parasite＇s hem...
关键词：Plasmodium falciparum hemoglobin uptake DYNAMIN INHIBITOR 
Amelioration of β^(654)-thalassemia in mouse model with the knockdown of aberrantly spliced β-globin mRNA被引量：1
《Journal of Genetics and Genomics》2008年第10期595-601,共7页Shuyang Xie Wei Li Zhaorui Ren Jingzhi Zhang Xinbin Guo Shu Wang Shuzhen Huang Fanyi Zeng Yi-Tao Zeng 
the National Basic Research Program of China (973 Program) (No 2004CB518806);the National High-tech R&D Program (863 Program) (No 2007AA021206);the National Natural Science Foundation of China (No 30571777);the Chinese National and Shanghai Leading Academic Disci-pline Project (No B204)
Large amounts of aberrantly spliced mRNA from the β^654 allele was present in erythroid cells, which might impair the erythropoiesis. A therapeutic strategy for β-thalassemia was explored by knocking down the aberra...
关键词：Β-THALASSEMIA small interfering RNA （siRNA） HEMOGLOBIN 
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