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  • 期刊=Signal Transduction and Targeted Therapyx
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2D4,a humanized monoclonal antibody targeting CD132,is a promising treatment for systemic lupus erythematosus
《Signal Transduction and Targeted Therapy》2024年第12期5693-5707,共15页Huiqi Yin Liming Li Xiwei Feng Zijun Wang Meiling Zheng Junpeng Zhao Xinyu Fan Wei Wu Lingyu Gao Yijing Zhan Ming Zhao Qianjin Lu 
supported by following fundings:the National Key R&D Program of China(No.2022YFC3601800);the CAMS Innovation Fund for Medical Sciences(No.2021-I2M-1-059);non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(No.2021-RC320-001,No.2020-RC320-003);the Special Program of National Natural Science Foundation of China(NO.32141004);the Special Research Fund for Central Universities,Peking Union Medical College(No.3332023075);Natural Science Foundation of Jiangsu Province(No.BK20230130);National Natural Science Foundation of China(No.82302982).
Current therapies for systemic lupus erythematosus that target a particular factor or cell type exhibit limited effectiveness.To address this limitation,our focus was on CD132,a subunit common to six inflammatory fact...
关键词：CD13 LUPUS ERYTHEMATOSUS 
How to package and SEND mRNA: a novel “humanized” vector system based on endogenous retroviruses
《Signal Transduction and Targeted Therapy》2021年第12期3367-3368,共2页Kristoffer Riecken Dawid Głów Boris Fehse 
This work has been supported by the Deutsche Forschungsgemeinschaft(DFG)within SFB841/SP2(80750187).
A recent publication in Science describes a novel mRNA delivery system termed SEND,entirely consisting of endogenous proteins.1 These virus-like particles(VLPs),able to deliver mRNA of e.g.,Cas9,represent a new class ...
关键词：ENDOGENOUS SYSTEM entirely 
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