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Long-term efficacy,safety and biocompatibility of a novel sirolimus eluting iron bioresorbable scaffold in a porcine model
《Bioactive Materials》2024年第9期135-146,共12页Ya-Nan Gao Hong-Tao Yang Zi-Feng Qiu Feng Qi Qian-Hong Lu Jian-Feng Zheng Zi-Wei Xi Xin Wang Li Li Gui Zhang De-Yuan Zhang Yu-Die Lu Hai-Ping Qi Hong Qiu Run-Lin Gao Yu-Feng Zheng 
supported by National Key R&D Program of China(grant number 2018YFC1106600);Shenzhen Industrial and Information Technology Bureau(20180309174916657);Science,Technology and Innovation Commission of Shenzhen Municipality(grant number GJHZ20180418190517302);Natural Science Foundation of China(grant number 52101282).
Iron is considered as an attractive alternative material for bioresorbable scaffolds(BRS).The sirolimus eluting iron bioresorbable scaffold(IBS),developed by Biotyx Medical(Shenzhen,China),is the only iron-based BRS w...
关键词：Bioresorbable scaffold Sirolimus eluting iron bioresorbable scaffold Preclinical study Completely bioresorbable Late lumen enlargement 
Challenges and strategies for in situ endothelialization and long-term lumen patency of vascular grafts被引量：14
《Bioactive Materials》2021年第6期1791-1809,共19页Yu Zhuang Chenglong Zhang Mengjia Cheng Jinyang Huang Qingcheng Liu Guangyin Yuan Kaili Lin Hongbo Yu 
This work was funded by the National Natural Science Foundation of China(82072396,81871490,81571022);Shanghai Collaborative Innovation Center for Translational Medicine(TM202010);Program of Shanghai Academic/Technology Research Leader(19XD1434500);Double Hundred Plan(20191819);the Research Fund of Medicine and Engineering of Shanghai Jiao Tong University(YG2017MS06).
Vascular diseases are the most prevalent cause of ischemic necrosis of tissue and organ,which even result in dysfunction and death.Vascular regeneration or artificial vascular graft,as the conventional treatment modal...
关键词：Vascular graft In situ endothelialization THROMBOGENESIS Intimal hyperplasia IMMUNOMODULATION 
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