ASTROCYTOMA

作品数:45被引量:65H指数:5
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相关领域:医药卫生生物学更多>>
相关作者:叶飞易伟薛德麟雷霆杨忠更多>>
相关机构:华中科技大学德阳市人民医院清华大学玉泉医院第三军医大学更多>>
相关期刊:《Open Journal of Modern Neurosurgery》《材料科学与工程(中英文A版)》《Chinese Medical Journal》《Neuroimmunology and Neuroinflammation》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Hypoxia-inducible factor 1alpha and vascular endothelial growth factor in Glioblastoma Multiforme:a systematic review going beyond pathologic implications
《Oncology Research》2024年第8期1239-1256,共18页DIMITRA P.VAGELI PANAGIOTIS G.DOUKAS KERASIA GOUPOU ANTONIOS D.BENOS KYRIAKI ASTARA KONSTANTINA ZACHAROULI SOTIRIS SOTIRIOU MARIA IOANNOU 
Glioblastoma multiforme(GBM)is an aggressive primary brain tumor characterized by extensive heterogeneity and vascular proliferation.Hypoxic conditions in the tissue microenvironment are considered a pivotal player le...
关键词:Glioblastoma multiforme(GBM) Astrocytoma Grade III Astrocytoma Grade IV Hypoxia-inducible factor 1alpha(HIF-1α) Vascular endothelial growth factor(VEGF) 
The interplay mechanism between IDH mutation, MGMT-promoter methylation, and PRMT5 activity in the progression of grade 4 astrocytoma: unraveling the complex triad theory
《Oncology Research》2024年第6期1037-1045,共9页MAHER KURDI ALAA ALKHOTANI ABDULRAHMAN SABBAGH EYAD FAIZO AHMED I.LARY AHMED K.BAMAGA MAJID ALMANSOURI BADR HAFIZ THAMER ALSHARIF SALEH BAEESA 
Background:The dysregulation of Isocitrate dehydrogenase(IDH)and the subsequent production of 2-Hydroxyglutrate(2HG)may alter the expression of epigenetic proteins in Grade 4 astrocytoma.The interplay mechanism betwee...
关键词:Grade 4 astrocytoma GLIOBLASTOMA Isocitrate dehydrogenase(IDH) O-6-methylguanine-DNA methyltransferase(MGMT) Protein methyltransferase proteins-5(PRMT5) Progression-free survival(PFS) 
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