DEFORMABILITY

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Single-cell electro-mechanical shear flow deformability cytometry
《Microsystems & Nanoengineering》2024年第6期235-247,共13页Junyu Chen Xueping Zou Daniel C.Spencer Hywel Morgan 
The complex structural and molecular features of a cell lead to a set of specific dielectric and mechanical properties which can serve as intrinsic phenotypic markers that enable different cell populations to be chara...
关键词：FLOW DEFORMED ELECTRICAL 
A deformability-based biochip for precise label-free stratification of metastatic subtypes using deep learning
《Microsystems & Nanoengineering》2023年第5期161-176,共16页Haojun Hua Shangjie Zou Zhiqiang Ma Wang Guo Ching Yin Fong Bee Luan Khoo 
supported in part by InnoHK Project on[Project 1-5 Multimodal spectroscopy(MMS)&biosensor platforms for monitoring CVDs]at Hong Kong Centre for Cerebro-cardiovascular Health Engineering(COCHE),in part by City University of Hong Kong(7020002,7005464,7005208,9667220);which is funded by the Research Grants Council(RGC),in part by Pneumoconiosis Compensation Fund Board(9211276);in part by Research Grants Council of the Hong Kong Special Administrative Region,China(CityU 21200921).
Cellular deformability is a promising biomarker for evaluating the physiological state of cells in medical applications.Microfluidics has emerged as a powerful technique for measuring cellular deformability.However,ex...
关键词：DEFORMABILITY METASTATIC PRECISE 
Microfluidic deformability-activated sorting of single particles被引量：2
《Microsystems & Nanoengineering》2020年第1期1258-1266,共9页Gihoon Choi Reza Nouri Lauren Zarzar Weihua Guan 
This work is partially supported by the National Science Foundation under Grant No.1710831,1902503,and 1912410.
Mechanical properties have emerged as a significant label-free marker for characterizing deformable particles such as cells.Here,we demonstrated the first single-particle-resolved,cytometry-like deformability-activate...
关键词：mechanism. PURITY INTEGRATE 
Stiffness increase of red blood cells during storage被引量：2
《Microsystems & Nanoengineering》2018年第1期484-489,共6页Zhensong Xu Yi Zheng Xian Wang Nadine Shehata Chen Wang Yu Sun 
financial support from the Natural Sciences and Engineering Research Council of Canada via an NSERC Steacie Memorial Fellowship and the Canada Research Chairs program.
In transfusion medicine,the deformability of stored red blood cells(RBCs)changes during storage in blood banks.Compromised RBC deformability can reduce the transfusion efficiency or intensify transfusion complications...
关键词：red blood cell effective stiffness DEFORMABILITY storage lesions MICROFLUIDICS 
Stiffening of sickle cell trait red blood cells under simulated strenuous exercise conditions被引量：2
《Microsystems & Nanoengineering》2016年第1期38-44,共7页Zhensong Xu Yi Zheng Xian Wang Nadine Shehata Chen Wang Shaorong Xie Yu Sun 
Financial support from the Natural Sciences and Engineering Research Council of Canada(NSERC)through a Steacie Fellowship,from Grand Challenges of Canada,and from the Canada Research Chairs Program is acknowledged.
The higher risk of vaso-occlusion events and sudden death for sickle-cell trait(SCT)athletes has been speculatively ascribed to SCT red blood cell(RBC)stiffening during strenuous exercise.However,the microenvironmenta...
关键词：DEFORMABILITY MICROFLUIDICS shear modulus sickle cell trait STIFFENING red blood cell 
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