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SINGLE-MOLECULE: 作品数：202被引量：198H指数：7; 导出分析报告; 相关作者：孙文彬刘凡新窦硕星詹鹏王鹏业更多>>; 相关机构：华南理工大学华中科技大学药用植物研究所北京大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划福建省自然科学基金北京市自然科学基金更多>>

Low-probability events detection using unsupervised multiprototype clustering for single-molecule electronics: 《Nano Research》2025年第4期402-410,共9页Chi Shang Rigong Te Shenglun Xiong Xipeng Liu Taige Lu Yixuan Zhu Chun Tang Jing Li Yu Zhou Haojie Liu Junyang Liu Wenjing Hong; supported by the National Key Research and Development Program of China(No.2024YFA1208103);the National Natural Science Foundation of China(Nos.22403079,22173075,22325303,21933012,and 22250003);the Fujian Provincial Department of Science and Technology(Nos.2022H6014 and 2023H6002);the Fundamental Research Funds for the Central Universities(Nos.20720220020 and 20720200068).; Artificial intelligence for science(AI4S)has emerged as a new horizon in state-of-the-art scientific research,and single-molecule electronics could be considered an ideal prototype in AI4S due to the opportunities in ...; 关键词：single-molecule electronics low-probability events detection machine learning artificial intelligence for science(AI4S)

Single-molecule Study Reveals that Sodium Alginate is Hydrophobic: 《Chinese Journal of Polymer Science》2025年第3期439-446,共8页Chen-Xi Gu Rui-Xue Li Wen-Tao Yuan Jiu-Long Zhou Yu-Xi Duan Yu Bao Shu-Xun Cui; financially supported by the National Natural Science Foundation of China(No.22273079)。; Sodium alginate(SA)is generally considered highly hydrophilic due to two hydroxyl groups and a carboxylate group on each pyranose ring.However,SA will form a gel after dissolving in water for a certain period.The two ...; 关键词：Sodium alginate HYDROPHOBICITY Inherent elasticity Single-molecule force spectroscopy

Digital PCR-free technologies for absolute quantitation of nucleic acids at single-molecule level: 《Chinese Chemical Letters》2025年第2期90-98,共9页Xinyi Luo Ke Wang Yingying Xue Xiaobao Cao Jianhua Zhou Jiasi Wang; supported by the National Key Research and Development Program of China(Nos.2023YFC2307305,2021YFF0703300);the Shenzhen Medical Research Fund(No.B2303003);Shenzhen Research Funding Program(Nos.JCYJ20220818102014028,RCBS20210609104339043);National Natural Science Foundation of China(No.22174167);Guangdong Basic and Applied Basic Research(No.2024A1515011281);Fundamental Research Funds for the Central Universities(No.24qnpy087)from Sun Yat-sen University。; Ultrasensitive detection of nucleic acids is of great significance for precision medicine.Digital polymerase chain reaction(dPCR)is the most sensitive method but requires sophisticated and expensive instruments and a ...; 关键词：Digital bioassay Isothermal amplification Nucleic acid detection Digital CRISPR CAS Absolute quantification

Single-molecule tracking in living microbial cells: 《Biophysics Reports》2025年第1期1-11,共11页Xiaomin Chen Qianhong Guo Jiexin Guan Lu Zhang Ting Jiang Liping Xie Jun Fan; supported by the National Key Research and Development Program of China(2023YFC3402400);National Natural Science Foundation of China(32101049,32271271 and 62205048);the Sichuan Science&Technology Program(2023NSFSC0638);NHC Key Laboratory of Nuclear Technology Medical Transformation(Mianyang Central Hospital)(2021HYX007)。; Some microbes are referred to as model organisms because they are easy to study in the laboratory and hold the ability to retain their characteristics during DNA replication,DNA transcription,and other fundamental pro...; 关键词：Single-molecule tracking PALM Diffusion coefficients TRAJECTORY Living microbial cells

Single-molecule techniques in studying the molecular mechanisms of DNA synapsis in non-homologous end-joining repair: 《Biophysics Reports》2025年第1期46-55,共10页Yuhao Jiang Chao Zhao Chenyang Zhang Weilin Li Di Liu Bailin Zhao; supported by the National Natural Science Foundation of China(22104120);the Three Qin Talents Introduction Program for Youths of Shaanxi Province(2023SYJ26);the Fundamental Research Funds for the Central Universities(xtr052023008);the“Young Talent Support Plan”of Xi’an Jiaotong University to Bailin Zhao;by the National Natural Science Foundation of China(32400427);the China Postdoctoral Science Foundation(2022M712546);the Fundamental Research Funds for the Central Universities(xzy012023018);the Postdoctoral Research Project of Shaanxi Province(2023BSHEDZZ07)to Di Liu;by the Fundamental Research Funds for the Central Universities(xzy022024035)to Chenyang Zhang。; DNA double-strand breaks(DSBs)are the most severe form of DNA damage,primarily repaired by the non-homologous end joining(NHEJ)pathway.A critical step in this process is DNA synapsis,where the two broken ends are brou...; 关键词：Single-molecule techniques smFRET Magnetic tweezers Non-homologous end joining(NHEJ) DNA Synapsis

“Pinching”aromatic molecules closer with optical tweezers in single-molecule junctions: 《Advanced Photonics》2025年第1期5-5,共1页Liwei Wang Shengxiong Xiao; π-πstacking,a fundamental noncovalent interaction between aromatic molecules,is essential for enabling charge transport across molecular fragments a process vital to both chemistry and biology.~(1,2)Owing to the wid...; 关键词：single molecule junctions designing targe applying mechanical forces modulating interaction optical tweezers noncovalent interaction STACKING aromatic moleculesis

Cucurbituril and cyclodextrin co-confinement-based multilevel assembly for single-molecule phosphorescence resonance energy transfer behavior: 《Chinese Chemical Letters》2024年第12期4-6,共3页Siwei Wang Wei-Lei Zhou Yong Chen; supported by National Natural Science Foundation of China(Nos.22101143 and 22361036);the China Postdoctoral Science Foundation(No.2021M691661);the Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region(No.NJYT22050);the Inner Mongolia Minzu University Doctoral Research Fund(No.BS554)。; Supramolecular assembly strategy has been proved to be an effective way to construct near-infrared(NIR)luminescent materials,especially the host-guest complexation involving macrocycles(such as cyclodextrin,cucurbitur...; 关键词：materials aggregation CYCLODEXTRIN

Multicolor single-molecule localization microscopy:review and prospect: 《PhotoniX》2024年第1期244-270,共27页Xi Chen Xiangyu Wang Fang Huang Donghan Ma; funded by the Natural Science Foundation of Liaoning Province(2023-MS-103),and the National Natural Science Foundation of China(62305041).; Single-molecule localization microscopy(SMLM)surpasses the diffraction limit by randomly switching fluorophores between fluorescent and dark states,precisely pinpointing the resulted isolated emission patterns,thereby...; 关键词：Super-resolution microscopy Singe-molecule localization microscopy Multicolor imaging DNA-PAINT Ratiometric imaging Spectroscopic imaging PSF engineering

Single-molecule characterization from the perspective of optics,photonics,and optoelectronics:a review: 《Advanced Photonics》2024年第6期34-54,共21页Qinghua Gao Zhizhuo Zhang Cong Zhao Zexiang Wang Yani Huo Dong Xiang Chuancheng Jia Xuefeng Guo; supported by the National Key R&D Program of China(Grant Nos.2021YFA1200102,2021YFA1200101,and 2022YFE0128700);the National Natural Science Foundation of China(Grant Nos.22173050,22150013,21727806,22273041,and 21933001);the Beijing National Laboratory for Molecular Sciences(Grant No.BNLMS-CXXM-202407);the Natural Science Foundation of Beijing(Grant No.2222009).; A singlemolecule is the building block of the material world and the smallest independently stable unit.Exploring single-molecule properties using optical,photonic,and optoelectronic techniques holds great scientific ...; 关键词：single molecules NANO-OPTICS PHOTONICS OPTOELECTRONICS ultrafast optics

Observation of single-molecule Raman spectroscopy enabled by synergic electromagnetic and chemical enhancement: 《PhotoniX》2024年第1期676-686,共11页Haiyao Yang Haoran Mo Jianzhi Zhang Lihong Hong Zhi-Yuan Li; supported by the National Natural Science Foundation of China(11974119);Science and Technology Project of Guangdong(2020B010190001);Guangdong Innovative and Entrepreneurial Research Team Program(2016ZT06C594);National Key R&D Program of China(2018YFA 0306200).; There has been a long fundamental pursuit to enhance and levitate the Raman scattering signal intensity of molecule by a huge number of~1415 orders of magnitude,to the level comparable with the molecule fluorescence i...; 关键词：SPECTROSCOPY ORDERS SPECTROSCOPY

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