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相关机构：北京大学香港大学中国农业大学中山大学更多>>
相关期刊：《Chinese Medical Journal》《Signal Transduction and Targeted Therapy》《Smart Molecules》《Chemical Research in Chinese Universities》更多>>
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Membraneless organelles in health and disease:exploring the molecular basis,physiological roles and pathological implications
《Signal Transduction and Targeted Therapy》2024年第12期5513-5538,共26页Yangxin Li Yuzhe Liu Xi-Yong Yu Yan Xu Xiangbin Pan Yi Sun Yanli Wang Yao-Hua Song Zhenya Shen 
supported by the National Natural Science Foundation of China(82370264 to Y.Li,82370501 to Y.H.S.,81870194 and 91849122 to Y.Li,92168203 to Z.S.);Project of State Key Laboratory of Radiation Medicine and Protection,Soochow University(No.GZK12023023 to Y.Li);Jiangsu Cardiovascular Medicine Innovation Center(CXZX202210);China Postdoctoral Science Foundation(No.2021M702394 to Y.W.);Jiangsu Funding Program for Excellent Postdoctoral Talent(No.2022ZB578 to Y.W.);.The project for the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);The National Key Research and Development Program of China(2022YFE0209700)to X.Y.Translational Research Grant of NCRCH(2020WSB07).
Once considered unconventional cellular structures,membraneless organelles(MLOs),cellular substructures involved in biological processes or pathways under physiological conditions,have emerged as central players in ce...
关键词：METABOLISM apparatus PHYSIOLOGICAL 
Predicting assembly mode of membraneless organelles by a FRET-based crowding sensor
《Signal Transduction and Targeted Therapy》2023年第7期3225-3227,共3页Feng Chen Siyuan Shen Xu Cao Liang Zhang Lunxu Liu Daoke Yang Yunyu Shi Wei He Xuebiao Yao Dan Liu 
This work was jointly supported by grants from the National Natural Science Foundation of China(32090041,D.L.);the Major Research Plan of the National Natural Science Foundation of China(2016YFA0101200,D.L.).This work was also supported in part by the CAS Key Laboratory of Innate Immunity and Chronic Disease.We are grateful to Prof.Yucai Wang and Prof.Chunlei Cang for providing experimental instruments and equipments,especially confocal microscopes.We appreciate Prof.Wei Xiong and Dr.Yushu Ge for their help and advice in the process of writing this letter.We thank Mr.Zhao Yue for his help in the data processing process.We also thank our colleagues Ms.Yun Wang,Ms.Mengtong Qin and Ms.Yu Chen for their help during the experiment.
Dear Editor,Biomacromolecules aggregate to form membraneless organelles(MLOs)via phase separation has been observed in a variety of physiological processes over the last decade.1 However,the molecular basis of biomacr...
关键词：SEPARATION methods MODE 
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