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PALIVIZUMAB: 作品数：13被引量：114H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王峥林洁董琳杨锡强赵晓东更多>>; 相关机构：天津医科大学温州医学院附属育英儿童医院重庆医科大学更多>>; 相关期刊：《World Journal of Cardiovascular Diseases》《中华儿科杂志》《德国临床用药》《World Journal of Clinical Pediatrics》更多>>

A protective human antibody against respiratory syncytial virus by targeting a prefusion epitope across sites IV and V of the viral fusion glycoprotein: 《hLife》2023年第1期12-25,共14页Lianpan Dai Jian Song Lili Xu Zhao Gao Senyu Xu Yan Chai Liang Wang Mi Yang Tong Ma Qihui Wang Sushan Cao Junming Yie Gang Zou Zhengde Xie Jim Zhen Wu George Fu Gao; supported by the National Natural Science Foundation of China(NSFC)(81991494 and 82122031);the National Key R&D Program of China(2020YFA0907100);the Chinese Academy of Sciences(YSBR-010);the CAMS Innovation Fund for Medical Sciences(CIFMS)(2019-I2M-5-026);Beijing Natural Science Foundation(L222076);L.D.is supported by the Youth Innovation Promotion Association CAS,China(2018113).; Respiratory syncytial virus(RSV)is one of the leading pathogens that cause lower respiratory tract infections in infants and the elderly.Passive immunoprophylaxis with monoclonal antibody(mAb)has been approved to prev...; 关键词：Respiratory syncytial virus(RSV)antibody RSV monoclonal antibody RSV fusion glycoprotein RSV epitope PALIVIZUMAB RSV prophylaxis

Effects of Palivizumab Guideline Changes on RSV Admissions in Patients with Congenital Heart Disease and Prematurity: 《World Journal of Cardiovascular Diseases》2021年第1期34-44,共11页John Pham Stephen Nageotte Jon Detterich Grace Kung; Background: Respiratory syncytial virus (RSV) causes significant morbidity and mortality in patients with a history of prem...; 关键词：2014 American Academy of Pediatrics Children Congenital Heart Disease Guidelines Infants PALIVIZUMAB PREMATURITY Respiratory Syncytial Virus

Application of the Probability Model for Starting Period to Initiate to Take Palivizumab by Prefecture Using National Official Sentinel Surveillance in Japan: 《Journal of Biosciences and Medicines》2020年第1期56-63,共8页Junko Kurita Tamie Sugawara Yasushi Ohkusa Michiko Nohara; Background: Palivizumab were used for the premature infant or a high-risk infant with congenital heart disease. However, recently outbreak pattern of respiratory syncytial (RS) virus infection has been varying year by...; 关键词：Respiratory Syncytial Virus Infection NATIONAL OFFICIAL SENTINEL Surveillance PALIVIZUMAB Probability Model STARTING PERIOD

Burden of respiratory syncytial virus infection in young children被引量：15: 《World Journal of Clinical Pediatrics》2012年第3期8-12,共5页Bernhard Resch; Respiratory syncytial virus(RSV) is the most frequent and important cause of lower respiratory tract infection in infants and children. It is a seasonal virus, with peak rates of infection occurring annually in the co...; 关键词：Children Epidemiology INFANT PALIVIZUMAB RESPIRATORY syncytial virus RESPIRATORY TRACT INFECTION Risk factors Vaccine

呼吸道合胞病毒感染的预防和治疗研究进展被引量：7: 《中华儿科杂志》2011年第11期865-868,共4页林洁董琳; 由于呼吸道合胞病毒（respiratory syncytial virus，RSV）感染所导致的沉重负担及高危儿童的病死率，对RSV感染的预防和治疗一直受到高度的重视。尽管如此，迄今尚无安全有效的疫苗问世，抗RSV单克隆抗体Palivizumab是目前经证实惟一...; 关键词：呼吸道合胞病毒感染预防药物 PALIVIZUMAB 治疗 RSV感染高危儿童单克隆抗体病死率

呼吸道合胞病毒逃逸株对单克隆抗体预防的抗性比较被引量：5: 《中华微生物学和免疫学杂志》2005年第8期648-651,共4页赵晓东 W.Sullender 杨锡强; 美国National Institutes of Health研究基金资助(R01A146495); 目的Palivizumab(PZ)是目前临床使用的惟一一个预防人类感染性疾病的单克隆抗体,本研究评估不同逃逸株在棉鼠体内对PZ预防的抗性。方法在细胞培养系统中筛选获得PZ逃逸株,测定其全长F基因序列,用微量中和法评估逃逸株对PZ的抗性,在棉鼠...; 关键词：呼吸道合胞病毒逃逸株 PALIVIZUMAB 预防 F基因病毒逃逸有效预防单克隆抗体呼吸道 WESTERN

RSV变异时不出现Palivizumab耐药: 《传染病网络动态》2004年第11期3-4,共2页宁慧娟; 据medscape．com9月3日报道(原载J Infect Dis 2004；190：975-978)，经常给早产儿应用palivizumab单克隆抗体以预防呼吸道合胞病毒(RSV)。; 关键词：PALIVIZUMAB 耐药性单克隆抗体呼吸道合胞病毒小儿

毛细支气管炎的诊治和预防进展被引量：82: 《国外医学（儿科学分册）》2003年第3期126-129,共4页王峥; 毛细支气管炎是婴幼儿急诊住院的常见病因,呼吸道合胞病毒(RSV)是最常见的病原体。近年发现,鼻病毒是其第二位病因。毛细支气管炎好发于冬季,发病高峰年龄在2～8个月。RSV通过呼吸道传播,对RSV感染的免疫反应包括体液免疫和细胞免疫。...; 关键词：毛细支气管炎婴幼儿呼吸道合胞病毒鼻病毒体液免疫细胞免疫静脉内免疫球蛋白 PALIVIZUMAB 疫苗

预防性应用Palivizumab能降低RSV感染住院率: 《河南医学研究》2002年第4期335-335,共1页; 关键词：预防性应用 PALIVIZUMAB RSV感染住院率儿童

抗呼吸道合胞病毒新型化疗剂被引量：3: 《国外医药（合成药．生化药．制剂分册）》2001年第5期271-272,共2页陈历胜陈本川; 关键词：抗呼吸道合胞病毒药新型化疗剂利巴韦林 PALIVIZUMAB 融合抑制剂

PALIVIZUMAB