TIPPING

作品数：60被引量：75H指数：5
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相关机构：西北工业大学西安电子科技大学安徽合力股份有限公司西安电子工程研究所更多>>
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Correction to‘Landscape dynamic network biomarker analysis reveals the tipping point of transcriptome reprogramming to prevent skin photodamage’
《Journal of Molecular Cell Biology》2022年第3期65-65,共1页Chengming Zhang Hong Zhang Jing Ge Tingyan Mi Xiao Cui Fengjuan Tu Xuelan Gu Tao Zeng Luonan Chen 
In the originally published version of this article(p.822),there was an error in the second affiliation of author Chengming Zhang.The erroneous affiliation was given as‘University of the Chinese Academy of Sciences’...
关键词：programming DAMAGE network 
Landscape dynamic network biomarker analysis reveals the tipping point of transcriptome reprogramming to prevent skin photodamage被引量：3
《Journal of Molecular Cell Biology》2021年第11期822-833,共12页Chengming Zhang Hong Zhang Jing Ge Tingyan Mi Xiao Cui Fengjuan Tu Xuelan Gu Tao Zeng Luonan Chen 
partially supported by the National Natural Science Foundation of China(31930022,31771476,12026608,12042104,and 11871456);the Strategic Priority Project of CAS(XDB38040400);the National Key R&D Program of China(2017YFA0505500);JST Moonshot R&D program(JP MJMS2021 to L.C.).
Skin,as the outmost layer of human body,is frequently exposed to environmental stressors including pollutants and ultraviolet(UV),which could lead to skin disorders.Generally,skin response process to ultraviolet B(UVB...
关键词：single-sample network tipping point UVB irradiation living skin equivalent model time series data skin lightening 
Hunt for the tipping point during endocrine resistance process in breast cancer by dynamic network biomarkers被引量：9
《Journal of Molecular Cell Biology》2019年第8期649-664,共16页Rui Liu Jinzeng Wang Masao Ukai Ki Sewon Pei Chen Yutaka Suzuki Haiyun Wang Kazuyuki Aihara Mariko Okada-Hatakeyama Luonan Chen 
This work was supported by grants from the National Key R&D Program of China (2017YFA0505500);Strategic Priority Research Program of the Chinese Academy of Sciences (XDBl3040700);the National Natural Science Foundation of China (11771152,91529303,31771476,31571363,31771469,91530320,61134013,81573023,81501203,and 11326035);Pearl River Science and Technology Nova Program of Guangzhou (201610010029);FISRT,Aihara Innovative Mathematical Modeling Project from Cabinet Office,Japan;Fundamental Research Funds for the Central Universities (2017ZD095);JSPS KAKENHI (15H05707);Grant-in-Aid for Scientific Research on Innovative Areas (3901) and SPS KAKENHI (15KT0084,17H06299,17H06302,and 18H04031);RIKEN Epigenome and Single Cell Project Grants to M.O.-H.This work was performed in part under the International Cooperative Research Program of Institute for Protein Research,Osaka University (ICRa-17-01 to L.C.and M.O.-H.).
Acquired drug resistance is the major reason why patients fail to respond to cancer therapies.It is a challenging task to deter.mine the tipping point of endocrine resistance and detect the associated molecules.Derive...
关键词：drug resistance breast cancer TIPPING POINT dynamic NETWORK biomarker (DNB) molecular NETWORK MRNA-SEQ 
Dysfunction of PLA2G6 and CYP2C44-associated network signals imminent carcinogenesis from chronic inflammation to hepatocellular carcinoma被引量：14
《Journal of Molecular Cell Biology》2017年第6期489-503,共15页Meiyi Li Chen Li Wei-Xin Liu Conghui Liu Jingru Cui Qingrun Li Hong Ni Yingcheng Yang Chaochao Wu Chunlei Chen Xing Zhen Tao Zeng Mujun zhao Lei Chen Jiarui Wu Rong Zeng Luonan Chen 
Little is known about how chronic inflammation contributes to the progression of hepatoceUular carcinoma （HCC）, especially the initiation of cancer. To uncover the critical transition from chronic inflammation to HC...
关键词：dynamical network biomarker inflammation-induced HCC critical transition early diagnosis high-grade dysplasticnodules tipping point 
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