supported by the National Natural Science Foundation of China,No. 81771228;Shanghai Association of Science and Technology,Nos. 22WZ2501700 and 23WZ2504500 (all to LY)
Bromodomain and plant homeodomain(PHD)finger containing protein 1(Brpf1)is an activator and scaffold protein of a multiunit complex that includes other components involving lysine acetyltransferase(KAT)6A/6B/7.Brpf1,K...
This work was supported by grants from the National Key R&D Program of China (2017YFA0505500);Strategic Priority Research Program of the Chinese Academy of Sciences (XDBl3040700);the National Natural Science Foundation of China (11771152,91529303,31771476,31571363,31771469,91530320,61134013,81573023,81501203,and 11326035);Pearl River Science and Technology Nova Program of Guangzhou (201610010029);FISRT,Aihara Innovative Mathematical Modeling Project from Cabinet Office,Japan;Fundamental Research Funds for the Central Universities (2017ZD095);JSPS KAKENHI (15H05707);Grant-in-Aid for Scientific Research on Innovative Areas (3901) and SPS KAKENHI (15KT0084,17H06299,17H06302,and 18H04031);RIKEN Epigenome and Single Cell Project Grants to M.O.-H.This work was performed in part under the International Cooperative Research Program of Institute for Protein Research,Osaka University (ICRa-17-01 to L.C.and M.O.-H.).
Acquired drug resistance is the major reason why patients fail to respond to cancer therapies.It is a challenging task to deter.mine the tipping point of endocrine resistance and detect the associated molecules.Derive...