supported by the Leading Investiga-tor Program of the Shanghai municipal government(17XD1401100);the National Key Basic Research Program(973 Program,2015CB554005)from the Ministry of Science and Technology of China,the National Natural Science Foundation of China(81871929,82072667 to C Huang,81871928 to H-C Sun);the Special Research Fund for Liver Cancer Diagnosis and Treatment from the China Anti-Cancer Association(H2020-044 to C Huang,H2020-008 to H-C Sun).
Dear Editor,Most patients with hepatocellular carcinoma(HCC)are diagnosed at an advanced stage and are ineligible for rad-ical surgery[1].As anti-programmed cell death protein 1(PD-1)monotherapy has not shown promisin...
This study was supported by a grant from the National Program on Key Basic Research Project (973 Program, 2003CB515501).
BACKGROUND: E-cadherin is an epithelial cell adhesion molecule, and decreased E-cadherin expression in liver cancer is associated with poor prognosis. A -160 C -> A polymorphism in the promoter region of E-cadherin ha...
supported by the National High Technology Research and Development Program of China(863 Program)(2001AA217011,2002AA2Z3352);the Major State Basic Research Development Program of China (973 Program)(G1998051004);the Science Foundation of Shanghai Municipal Government(02DJ14056)to JingDe ZHU.
To determine the possible role of the epigenetic mechanisms in carcinogenesis of the hepatocellular carcinoma, we methylation-profiled the promoter CpG islands of twenty four genes both in HCC tumors and the neighbori...