This work was supported by grants from the National Key Basic Research Program of China(2013CB531100 to Y.-H.C.);the National Natural Science Foundation of China for National Innovative Research Groups(81221001 to Y.-H.C.);the Major International Joint Research Program of China(81120108004 to Y.-H.C.);the Youth Program(81100124 to L.X.);the General Program(81170224 and 81270313 to J.L.and 31271214 to Y.-H.C.)of the National Natural Science Foundation of China.
The mammalian nuclear pore complex is comprised of∼30 different nucleoporins(Nups).It governs the nuclear import of gene expression modulators and the export of mRNAs.In cardiomyocytes,Na1-H1 exchanger-1(NHE1)is an i...