AMANTADINE

作品数:13被引量:29H指数:2
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相关领域:医药卫生更多>>
相关作者:潘万龙张静陈幽婷王德广刘芳更多>>
相关机构:徐州医科大学徐州医学院北京理工大学更多>>
相关期刊:《Advances in Parkinson's Disease》《中华物理医学与康复杂志》《Chinese Journal of Chemistry》《Acta Pharmacologica Sinica》更多>>
相关基金:国家自然科学基金更多>>
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Discovery of amantadine formate:Toward achieving ultrahigh pyroelectric performances in organics
《The Innovation》2022年第2期73-78,共6页Junyan Zhou Shifeng Jin Congcong Chai Munan Hao Xin Zhong Tianping Ying Jiangang Guo Xiaolong Chen 
This work is financially supported by the National Key Research and Development Program of China(2018YFE0202600,2016YFA0300301),the National Natural Science Foundation of China under granting numbers:No.51532010,91422303,51772323;and the Key Research Program of Frontier Sciences,CAS,Grant No.QYZDJ-SSW-SLH013.
Pyroelectrics are a class of polar compounds that output electrical signals upon changes in temperature.With the rapid development of flexible electronics,organic pyroelectrics are highly desired.However,most organics...
关键词:temperature REALIZATION electrical 
Sensitive and rapid determination of amantadine without derivatization in human plasma by LC–MS/MS for a bioequivalence study被引量:10
《Journal of Pharmaceutical Analysis》2018年第3期202-207,共6页Abhaysingh Bhadoriya Shivprakash Rathnam Bhavesh DasANDi Dharmesh Parmar Mallika Sanyal Pranav S.Shrivastav 
A highly sensitive, rapid and rugged liquid chromatography-tandem mass spectrometw (LC-ESI-MS/MS) method was developed for reliable estimation of amantadine (AMD), an antiviral drug in human plasma. The analyte an...
关键词:AMANTADINE Amantadine-d6 LC-ESI-MS/MS SENSITIVE Bioequivalence study Human plasma 
Comparison of the Analgesic Activity of Antiparkinsonian Aminoadamantane Derivatives Amantadine and Hemantane
《Advances in Parkinson's Disease》2016年第3期50-60,共12页Elena Ivanova Inga Kapitsa Elena Valdman Tatyana Voronina 
The efficacy of some aminoadamantane derivatives used as neurodegeneration treatments is due to their ability to block NMDA receptors. But this mechanism of pharmacological action can also produce analgesic activity. ...
关键词:NMDA Receptor Antagonists Tail-Flick Test Acetic Twitches Formalin Test Exudative Inflammation 
Direct-acting Antivirals and Host-targeting Agents against the Hepatitis A Virus被引量:1
《Journal of Clinical and Translational Hepatology》2015年第3期205-210,共6页Tatsuo Kanda Shingo Nakamoto Shuang Wu Masato Nakamura Xia Jiang Yuki Haga Reina Sasaki Osamu Yokosuka 
Hepatitis A virus (HAV) infection is a major cause of acute hepatitis and occasionally leads to acute liver failure in both developing and developed countries.Although effective vaccines for HAV are available,the deve...
关键词:AMANTADINE DAA HAV HTA La protein Drug overview 
Use of Graphene and Cucurbit[7]uril Electrodes for the Determination of Amantadine in Biological Fluids被引量:2
《American Journal of Analytical Chemistry》2015年第7期623-630,共8页C. S. H. Domínguez P. Hernández 
A differential pulse voltammetry (DPV) method for amantadine (AT) determination is developed. To this end, all the chemical and instrumental variables affecting the determination of amantadine are optimized. These stu...
关键词:GLASSY-CARBON Electrode AMANTADINE Differential Pulse VOLTAMMETRY Human URINE 
Amantadine, aggression and irritability after brain injury
《中华物理医学与康复杂志》2014年第10期760-760,共1页
关键词:创伤性脑损伤 金刚烷胺 后遗症 随机化 
Determination of Amantadine Residue in Honey by Solid-phase Extraction and High-performance Liquid Chromatography with Pre-column Derivatization and Fluorometric Detection被引量:15
《Chinese Journal of Chemistry》2011年第8期1764-1768,共5页张金振 赵静 周金慧 薛晓峰 李熠 吴黎明 陈芳 
Amantadine (AMA) is an anti-viral drug used in apiculture to protect honeybee against the sacbrood virus (Morator aetatulae). This study described a reliable high-performance liquid chromatographic (HPLC) method...
关键词:AMANTADINE HONEY solid-phase extraction high-performance liquid chromatographic (HPLC) fluorometric detection 
Ion Channels as Antivirus Targets
《Virologica Sinica》2010年第4期267-280,共14页Xin LIANG Zhi-yuan LI 
Ion channels are membrane proteins that are found in a number of viruses and which are of crucial physiological importance in the viral life cycle. They have one common feature in that their action mode involves a cha...
关键词:Viral ion channel Antiviral therapy Viruses AMANTADINE 
Flu channel drug resistance:a tale of two sites
《Protein & Cell》2010年第3期246-258,共13页Rafal M.Pielak James J.Chou 
We thank Matthew Call for insightful discussion and critical reading of the manuscript.This work was supported by the NIH grant AI054520(to JJC).
The M2 proteins of influenza A and B virus,AM2 and BM2,respectively,are transmembrane proteins that oligomerize in the viral membrane to form proton-selective channels.Proton conductance of the M2 proteins is required...
关键词:M2 BM2 influenza proton channel AMANTADINE rimantadine 
Amantadine as a regulator of internal ribosome entry site
《Acta Pharmacologica Sinica》2008年第11期1327-1333,共7页Ying-ju CHEN Shih-jhan ZENG John TA HSU Jim-tong HORNG Hong-ming YANG Shin-ru SHIH Yu-ting CHU Tzong-yuan WU 
Aim: Studies of eukaryotes have yielded 2 translation initiation mechanisms: a classical cap-dependent mechanism and a cap-independent mechanism proceeding through the internal ribosomal entry site (IRES). We hypo...
关键词:AMANTADINE Enterovirus 71 internal ribosomeentry site riboswich 
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