This work is financially supported by the National Key Research and Development Program of China(2018YFE0202600,2016YFA0300301),the National Natural Science Foundation of China under granting numbers:No.51532010,91422303,51772323;and the Key Research Program of Frontier Sciences,CAS,Grant No.QYZDJ-SSW-SLH013.
Pyroelectrics are a class of polar compounds that output electrical signals upon changes in temperature.With the rapid development of flexible electronics,organic pyroelectrics are highly desired.However,most organics...
A highly sensitive, rapid and rugged liquid chromatography-tandem mass spectrometw (LC-ESI-MS/MS) method was developed for reliable estimation of amantadine (AMD), an antiviral drug in human plasma. The analyte an...
The efficacy of some aminoadamantane derivatives used as neurodegeneration treatments is due to their ability to block NMDA receptors. But this mechanism of pharmacological action can also produce analgesic activity. ...
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A differential pulse voltammetry (DPV) method for amantadine (AT) determination is developed. To this end, all the chemical and instrumental variables affecting the determination of amantadine are optimized. These stu...
Amantadine (AMA) is an anti-viral drug used in apiculture to protect honeybee against the sacbrood virus (Morator aetatulae). This study described a reliable high-performance liquid chromatographic (HPLC) method...
Ion channels are membrane proteins that are found in a number of viruses and which are of crucial physiological importance in the viral life cycle. They have one common feature in that their action mode involves a cha...
We thank Matthew Call for insightful discussion and critical reading of the manuscript.This work was supported by the NIH grant AI054520(to JJC).
The M2 proteins of influenza A and B virus,AM2 and BM2,respectively,are transmembrane proteins that oligomerize in the viral membrane to form proton-selective channels.Proton conductance of the M2 proteins is required...
Aim: Studies of eukaryotes have yielded 2 translation initiation mechanisms: a classical cap-dependent mechanism and a cap-independent mechanism proceeding through the internal ribosomal entry site (IRES). We hypo...