support from the Natural Science Foundation of Henan Province(grant no.212300410152);the Key Scientific and Technological Project of Henan Province(grant no.212102110439);Henan University of Animal Husbandry and Economy(grant no.2019HNUAHEDF011 and XKYCXJJ2020006);the Key Scientific Research Project for Colleges and Universities of Henan Province(grant no.22B150005)。
A novel and efficient[3+2]annulation of 2-substituted aziridines and N-tosyl cyanamides via a dominoregioselective ring-opening/5-exo-dig cyclization procedure has been developed,allowing the directpreparation of N_(2...
supported by the National Nature Science Foundation of China(Nos.21576195 and 21776207)
In this study, we applied a novel, mild, and convenient synthetic method involving the oxidative cyclization of 1-(pyrazin-2-yl)guanidine derivatives to produce [1,2,4]triazolo[4,3-a ]pyrazin-3-amines. We optimized th...