云南高校图书馆联盟文献共享服务平台- GUANIDINES

GUANIDINES: 作品数：11被引量：27H指数：2; 导出分析报告; 相关领域：理学更多>>; 相关作者：陈晓玲黄善生李文斌周爱民王新良更多>>; 相关机构：河北医科大学上海大学更多>>; 相关期刊：《Organic Chemistry Frontiers》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Chinese Medical Journal》更多>>; 相关基金：国家自然科学基金河南省自然科学基金更多>>

Direct synthesis of N_(2)-unprotected five-memberedcyclic guanidines by regioselective[3+2]annulation of aziridines and cyanamides: 《Organic Chemistry Frontiers》2022年第6期1574-1579,共6页Chuan-Chuan Wang Xin-Lu Wang Qing-Ling Zhang Juntao Liu Zhi-Wei M Zhi-Jing Liu Ya-Jing Chen; support from the Natural Science Foundation of Henan Province(grant no.212300410152);the Key Scientific and Technological Project of Henan Province(grant no.212102110439);Henan University of Animal Husbandry and Economy(grant no.2019HNUAHEDF011 and XKYCXJJ2020006);the Key Scientific Research Project for Colleges and Universities of Henan Province(grant no.22B150005)。; A novel and efficient[3+2]annulation of 2-substituted aziridines and N-tosyl cyanamides via a dominoregioselective ring-opening/5-exo-dig cyclization procedure has been developed,allowing the directpreparation of N_(2...; 关键词：membered protected GUANIDINE

Facile Synthesis of [1,2,4]Triazolo[4,3-a]pyrazin-3-amines via Oxidative Cyclization of 1-(Pyrazin-2-yl)guanidine Derivatives: 《Transactions of Tianjin University》2019年第2期185-194,共10页Wei Li Jieqiong Kang Xueqin Zhou Dongzhi Liu Haiya Sun Fang Xu Tianyang Wang; supported by the National Nature Science Foundation of China(Nos.21576195 and 21776207); In this study, we applied a novel, mild, and convenient synthetic method involving the oxidative cyclization of 1-(pyrazin-2-yl)guanidine derivatives to produce [1,2,4]triazolo[4,3-a ]pyrazin-3-amines. We optimized th...; 关键词：Triazolopyrazines [1 2 4]Triazolo[4 3-a]pyrazin-3-amines 1-(Pyrazin-2-yl)guanidines CYCLIZATION Synthesis

Chiral organobases: Properties and applications in asymmetric catalysis被引量：1: 《Chinese Chemical Letters》2018年第8期1201-1208,共8页Weidi Cao Xiaohua Liu Xiaoming Feng; the National Natural Science Foundation of China (Nos. 21625205 and 21332003);the National Program for Support of Top-Notch Young Professionals for financial support; Chiral organobases occupy a significant position in asymmetric organocatalysis. The general types of chiral organobases include tertiary amines, amidines, guanidines, cyclopropenimines, and iminophosphoranes, etc. The...; 关键词：Chiral organobases Asymmetric organocatalysis AMINES AMIDINES GUANIDINES Cyclopropenimines Iminophosphoranes

N<sup>ω</sup>-Nitro-N<sup>ω’</sup>-Substituted Guanidines: A Simple Class of Nitric Oxide Synthase Inhibitors: 《Modern Research in Inflammation》2014年第2期48-58,共11页Christophe D. Guillon David D. Wisnoski Jaya Saxena Ned D. Heindel Diane E. Heck Donald J. Wolff Jeffrey D. Laskin; A series of Nω-nitro-Nω’-substituted guanidines has been prepared as potential inhibitors of the human Nitric Oxide Synthase (NOS) isoforms. The reported utility of amino-guanidine and nitroarginine in iNOS inhibit...; 关键词：Nitro-Guanidines Nitric Oxide SYNTHASE (NOS) ISOFORMS Selective Inhibitors

Synthesis of Guanidines from Amines and Carbodiimides Catalyzed by Mono-lndenyI-Ligated Rare Earth Metal Bis（silylamide） Complexes被引量：1: 《Chinese Journal of Chemistry》2013年第8期1065-1071,共7页; Nucleophilic addition of primary aromatic amines to carbodiimides in the presence of catalytic amount of the mono-indenyl-ligated rare earth metal bis（silylamide） complexes （C9H6CMe2CHzCsH4N-a）Ln[N（SiHMe2）2]2 at...; 关键词：rare earth amide complex AMINE CARBODIIMIDE guanylation catalysis

Aluminum chloride:A highly efficient catalyst for addition of amines to carbodiimides to synthesize substituted guanidines被引量：2: 《Chinese Science Bulletin》2012年第26期3419-3422,共4页ZHU XueHua XU Fan SHEN Qi; supported by the National Natural Science Foundation of China (20972107,20872106);the Department of National Education PhD Foundation;the Priority Academic Program Development of Jiangsu Higher Education Institutions; A catalytic addition of amine N H bonds to carbodiimides using aluminum chloride as a Lewis acid catalyst is developed.The reaction proceeds under mild conditions without solvent to afford a series of substituted guan...; 关键词：碳化二亚胺三氯化铝高效催化剂路易斯酸催化剂合成原位红外光谱胍催化加成

Role of endogenous peroxynitrite in pulmonary injury and fibrosis induced by bleomycin A_5 in rats: 《Acta Pharmacologica Sinica》2003年第7期75-80,105,共7页陈晓玲李文斌周爱民艾洁黄善生; AIM: To observe the role of endogenous peroxynitrite （ONOO^-） in pulmonary injury and fibrosis induced by bleomycin A₅ （BLM-A₅） in rats. METHODS: Pulmonary injury and fibrosis of ra...; 关键词：peroxynitrous acid BLEOMYCIN TOXICITY pulmonary fibrosis GUANIDINES

Hyper-polyhedron model applied to molecular screening of guanidines as Na/H exchange inhibitors: 《Acta Pharmacologica Sinica》2003年第5期472-476,480,共6页包新华陆文聪刘亮陈念贻; Project supported by Ford-China Foundation, № 9716214.; AIM: To investigate structure-activity relationships of N-(3-Oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl) guanidines in Na/H exchange inhibitory activities and probe into a new method of the computer-aided molecul...; 关键词：GUANIDINES structure-activity relationship sodium-hydrogen antiporter pattern recognition hyperpolyhedron models

Inhibitory effect of aminoguanidine on bleomycin-induced pulmonary toxicity in rat: 《Acta Pharmacologica Sinica》2001年第8期711-715,共5页陈晓玲黄善生李文斌王殿华王新良; AIM: To observe the inhibitory effect of aminoguanidin (AG) on the pulmonary toxicity induced by bleomycin A5(BLM-A5) in rat. METHODS: The contents of hy-droxyproline, nitrite/nitrate (NO2/NO3 ), and malondi-aldehyde ...; 关键词：BLEOMYCIN TOXICITY pulmonary fibrosis GUANIDINES

Effects of aminoguanidine on nitric oxide production induced by inflammatory cytokines and endotoxin in cultured rat hepatocytes被引量：20: 《World Journal of Gastroenterology》2001年第3期331-334,共4页Guo Liang Zhang Ye Hong Wang Hui Ling Teng Zhi Bin Lin Department of Pharmacology,School of Basic Medical Sciences,Beijing University,Beijiog 100083,ChinaDr.Guo Liang Zhang graduated from Xinxiang Medical College in 1982,got Ph.D.at Nagoya City University Medical School,Japan in 1994,finished postdoctoral research at Beijing Medical Univcrsity in 1996,now an associate professor of pharmacology,specialized in hepatic pharmacology,having 15 papers published.; Project supported by the National Natural Science Foundation of China,No.39770861.and JANSSEN Science Research Foundation.; AIM: To study the effects of aminoguanidine (AG) and two L-arginine analogues N(omega)-nitro-L-arginine methyl ester (L-NAME) and N(omega)-nitro-L-arginine (L-NNA) on nitric oxide (NO) production induced by cytokines ...; 关键词：Animals Antineoplastic Agents Cells Cultured Comparative Study Cyclic GMP Cytokines DACTINOMYCIN Dexamethasone Enzyme Inhibitors Glucocorticoids GUANIDINES Hepatocytes Interferon Type II INTERLEUKIN-1 LIPOPOLYSACCHARIDES Male NG-Nitroarginine Methyl Ester Nitric Oxide Nitric Oxide Synthase inhibitors Nitroarginine Protein Synthesis Inhibitors RATS Rats Wistar Research Support Non-U.S. Gov't Tumor Necrosis Factor-alpha

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