the National Natural Science Foundation of China(22071171);the Natural Science Foundation of Zhejiang Province(LZ22B020003)for financial support of this work.
Comprehensive Summary The development of switchable solvent-free multicomponent reactions to build high-value-added products is an important demand for organic synthesis.Herein,we detailed the successful implementatio...
the National Natural Science Foundation of China(No.22078150);the National Key R&D Program of China(No.2021YFC2101904);the Jiangsu Province Industrial Prospects and Key Core Technologies-Competitive Projects(No.BE2021083);the Nanjing International Joint R&D Project(No.202002037)for their financial support。
An iron-catalyzed[4+2]annulation of amidines with α,β-unsaturated ketoxime acetates is described.This strategy employs amidines as CN units and provides a new protocol for the construction of 2,4,6-trisubstituted py...
the National Natural Science Foundation of China (No. 22078150);the Natural Science Foundation of Jiangsu Province, Frontier Project (No. BK20212003)
The electrooxidative[3+2]annulation of amidines with 2-arylideneindane-1,3-diones or 4-alkylidene pyrazolones is reported using NaI as a redox catalyst and electrolyte under constant current electrolysis in an undivid...
the financial support from National Natural Science Foundation of China(No.22001121 and 21772093);Natural Science Foundation of Jiangsu Province(BK20180690);National Students’Platform for Innovation and Entrepreneurship Training Program(202110291019Z);Nanjing Tech University(Start-up Grant No.39837118 and 39837146).
An efficient defluorinative net-[3+3]-cyclization strategy for the construction of perfluoroalkyl-substituted pyrimidine derivatives by using a series of perfluoroalkyl alkynes and amidines as starting materials was d...
the financial support from the National Natural Science Foundation of China(21772122);the Shuguang program(20SG44)from the Shanghai Education Development Foundation and the Shanghai Municipal Education Commission;the“111”Innovation and Talent Recruitment Base on Photochemical and Energy Materials(No.D18020);the Shanghai Engineering Research Center of Green Energy Chemical Engineering(No.18DZ2254200).
An iron-catalyzed dearomative amination of β-naphthols via a nitrene-transfer process has been developed.Oxadiazolones,which have rarely been applied for the synthesis of amidines,are used as the nitrene source.A var...
A novel generation of oxazole vlide and interception with sulfonamide have been well developed to construct fully substituted amidines. This copper-catalyzed four-component reaction incorporates two diazo molecules to...
the National Natural Science Foundation of China (Nos. 21625205 and 21332003);the National Program for Support of Top-Notch Young Professionals for financial support
Chiral organobases occupy a significant position in asymmetric organocatalysis. The general types of chiral organobases include tertiary amines, amidines, guanidines, cyclopropenimines, and iminophosphoranes, etc. The...
supported by the National Natural Science Foundation of China(No.51102114)
The synthesis of 1,3,5-substituted-1,2,4-triazoles from α-imino-3-pyridine formic acid,acetamidine and anisole hydrazine as a model reaction in this paper and the synthesis mechanism of 1,3,5-substituted-1,2,4-triazo...
The management of neurological disorders have huge and increasing human and economic costs. Despite this, there is a scarcity of effective therapeutics, and there is an extreme urgency for new and real treatments. In ...
the China Postdoctoral Science Foundation Funded Project (No. 2014M562165);Jiangxi Natural Science Foundation (Nos. 20133BCB24011, 20141BBG70070 and 20151BAB203011);the Science Foundation of Jiangxi Provincial Department of Education (No. Gjj4669) for support of this research
A direct metal-free C-H amination reaction of cinnamaldehydes and amidines to realize the synthesis of polysubstituted pyrimidines was developed in the presence of base. This greener synthetic methodology provides a s...