DACTINOMYCIN

作品数:5被引量:22H指数:2
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相关领域:医药卫生更多>>
相关作者:向阳杨隽钧更多>>
相关机构:北京协和医院更多>>
相关期刊:《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Case Reports in Clinical Medicine》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》更多>>
相关基金:国家自然科学基金更多>>
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Chemotherapy initiation with single-course methotrexate alone or combined with dactinomycin versus multi-course methotrexate for low-risk gestational trophoblastic neoplasia: a multi-centric randomized clinical trial被引量:2
《Frontiers of Medicine》2022年第2期276-284,共9页Lili Chen Ling Xi Jie Jiang Rutie Yin Pengpeng Qu Xiuqin Li Xiaoyun Wan Yaxia Chen Dongxiao Hu Yuyan Mao Zimin Pan Xiaodong Cheng Xinyu Wang Qingli Li Danhui Weng Xi Zhang Hong Zhang Quanhong Ping Xiaomei Liu Xing Xie Beihua Kong Ding Ma Weiguo Lu 
We aimed to evaluate the effectiveness and safety of single-course initial regimens in patients with low-risk gestational trophoblastic neoplasia(GTN).In this trial (NCT01823315),276 patients were analyzed.Patients we...
关键词:gestational trophoblastic neoplasia(GTN) methotrexate(MTX) dactinomycin(ACTD) 
Toxic epidermal necrolysis after dactinomycin and vincristine combination chemotherapy for nephroblastoma
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2017年第7期649-652,共4页Yuan LIANG Zhou YANG Zi-gang XU Lin MA 
Project supported by the Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding(No.ZYLX201601);the Project of Excellent Talents in Beijing City(No.2013A003034000013);the National Natural Science Foundation of China(No.81602754)
In this study, we describe a 2-year-old boy patient with nephroblastoma who has developed toxic epidermal necrolysis (TEN) associated with the combination chemotherapy administration of dactinomycin and vincristine....
关键词:药疹 恶性肿瘤 中毒性表皮坏死松解症 化疗 肾母细胞瘤 
Toxic Effect of Chemotherapy (Even When Used in Conventional Dose) and Dealing with That Toxicity Effectively: A Case Report
《Case Reports in Clinical Medicine》2017年第4期127-131,共5页Lijin Qiong Mohammad Arphan Azaad Yongping Li 
Background: Use of Chemotherapy is a double edged sword apart from destroying malignant cells it also has life threatening complications, so clinician should be ready to counter the complication while also dealing wit...
关键词:INVASIVE MOLE 5 Fluorourail DACTINOMYCIN 
Altered subcellular distribution of nucleolar protein fibrillarin by actinomycin D in HEp-2 cells
《Acta Pharmacologica Sinica》2004年第7期902-906,共5页MinCHEN PingJIANG 
Supported by the Doctoral Foundation of Jiangsu University No 2681280006.
AIM: To study the effects of actinomycin D on subcellular distribution ofnucleolar protein fibrillarin in HEp-2 (human esophageal epithelial type 2) cells, and molecularmechanisms for maintenance of fibrillarin in nuc...
关键词:DACTINOMYCIN nuclear proteins fluorescence antibody technique immunoblotting 
Effects of aminoguanidine on nitric oxide production induced by inflammatory cytokines and endotoxin in cultured rat hepatocytes被引量:20
《World Journal of Gastroenterology》2001年第3期331-334,共4页Guo Liang Zhang Ye Hong Wang Hui Ling Teng Zhi Bin Lin Department of Pharmacology,School of Basic Medical Sciences,Beijing University,Beijiog 100083,ChinaDr.Guo Liang Zhang graduated from Xinxiang Medical College in 1982,got Ph.D.at Nagoya City University Medical School,Japan in 1994,finished postdoctoral research at Beijing Medical Univcrsity in 1996,now an associate professor of pharmacology,specialized in hepatic pharmacology,having 15 papers published. 
Project supported by the National Natural Science Foundation of China,No.39770861.and JANSSEN Science Research Foundation.
AIM: To study the effects of aminoguanidine (AG) and two L-arginine analogues N(omega)-nitro-L-arginine methyl ester (L-NAME) and N(omega)-nitro-L-arginine (L-NNA) on nitric oxide (NO) production induced by cytokines ...
关键词:Animals Antineoplastic Agents Cells  Cultured Comparative Study Cyclic GMP Cytokines DACTINOMYCIN Dexamethasone Enzyme Inhibitors Glucocorticoids GUANIDINES Hepatocytes Interferon Type II INTERLEUKIN-1 LIPOPOLYSACCHARIDES Male NG-Nitroarginine Methyl Ester Nitric Oxide Nitric Oxide Synthase inhibitors Nitroarginine Protein Synthesis Inhibitors RATS Rats  Wistar Research Support  Non-U.S. Gov't Tumor Necrosis Factor-alpha 
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