This work was supported by the National Natural Science Foundation of China(grant No.30730022);the National Basic Research Program(973 Program)(grant Nos.2006CB806503 and 2007CB914304);the National Programs for High Technology Research and Development Program(863 Program)(grant Nos.2006AA02A322 and 2006AA020502);the CAS(China)grant KSCX2-YW-R-05 to Z.R.
Nascent polypeptide associated complex(NAC)and its two isolated subunits,αNAC and βNAC,play important roles in nascent peptide targeting.We determined a 1.9Åresolution crystal structure of the interaction core of NA...