HOMODIMER

作品数：9被引量：11H指数：2
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相关领域：生物学医药卫生更多>>
相关机构：四川大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《Plant Communications》《Bioresources and Bioprocessing》《Acta Biochimica et Biophysica Sinica》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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Non-affinity platform for processing knob-into-hole bispecific antibody
《Bioresources and Bioprocessing》2024年第1期1447-1457,共11页Xiaoyang Wang Min Li Mengting Li Huoyan Hong Kai Gao Puya Zhao 
Bispecific antibodies hold significant potential as next-generation biotherapeutics owing to their ability to simultaneously bind to two targets.However,the development of bispecific antibodies as biotherapeutics has ...
关键词：Bispecific antibodies Non-protein A purification BYPRODUCTS HOMODIMER 
Structural characterizations of protonated homodimers of amino acids:Revealed by infrared multiple photon dissociation(IRMPD) spectroscopy and theoretical calculations被引量：3
《Chinese Chemical Letters》2018年第9期1333-1339,共7页Lifu Ma Juan Ren Ruxia Feng Kailin Zhang Xianglei Kong 
supported by the National Natural Science Foundation of China(Nos.21475065,21627801 and 11704280)
Infrared multiple photon dissociation （IRMPD） spectroscopic and theoretical studies of protonated homodimers of amino acids generated by electrospray ionization in the gas phase have been reviewed. Results show that...
关键词：Amino acid HOMODIMER IRMPD spectroscopy Proton affinity Charge-solvated Salt-bridged ESI mass spectrometry 
Crystal structure of a novel non-Pfam protein PF2046 solved using low resolution B-factor sharpening and multi-crystal averaging methods
《Protein & Cell》2010年第5期453-458,共6页Jing Su Yang Li Neil Shaw Weihong Zhou Min Zhang Hao Xu Bi-Cheng Wang Zhi-Jie Liu 
This work was funded by the Ministry of Science and Technology of China(Grant Nos.2006AA02A316,2009DFB30310 and 2006CB910901);the National Natural Science Foundation of China(Grants Nos.30670427 and 30721003);the Ministry of Health of China(Grant No.2008ZX10404);CAS Research Grant(No.KSCX2-YW-R-127 and INFO-115-D01-2009).
Sometimes crystals cannot diffract X-rays beyond 3.0Åresolution due to the intrinsic flexibility associated with the protein.Low resolution diffraction data not only pose a challenge to structure determination,but als...
关键词：low resolution diffraction PF2046 Bfactor sharpening a homodimer of trimers 
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