MACROLIDE

作品数:32被引量:76H指数:4
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相关领域:医药卫生理学更多>>
相关作者:夏曦李少丽李建成丁双阳江海洋更多>>
相关机构:中国农业大学首都儿科研究所中国科学院更多>>
相关期刊:《Acta Pharmacologica Sinica》《Chinese Medical Journal》《Advances in Microbiology》《World Journal of Pediatrics》更多>>
相关基金:国家自然科学基金北京市自然科学基金“十一五”国家科技支撑计划The Royal Society更多>>
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  • 期刊=Cancer Pathogenesis and Therapyx
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Carrimycin,a first in-class anti-cancer agent,targets selenoprotein H to induce nucleolar oxidative stress and inhibit ribosome biogenesis被引量:1
《Cancer Pathogenesis and Therapy》2023年第2期111-115,共5页LaYow C.Yu Danielle D.Dang Sophie Zhuang Shuran Chen Zhengping Zhuang Jared S.Rosenblum 
supported in part by the Intramural Program of the NCI and NINDS(National Institutes of Health)and did not receive any specific grant from funding agencies(e.g.,public,commercial,or not-forprofit sectors)outside of the authors'academic institution.
Carrimycin is a synthetic macrolide antibiotic that has been shown to have anti-cancer activity;however,its exact mechanism of action and molecular target were previously unknown.It was recently elucidated that Isoval...
关键词:SELENOPROTEIN Ribosome biogenesis MACROLIDE Cancer Carrimycin 
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