supported by the Natural Science Foundation of Jiangsu Province(No.BK20201332);the“Double First-Class”University Project(No.CPU2018GF03);the Six Talent Peaks Project of Jiangsu Province(No.SWYY-107);Jiangsu Province‘333’Project,111 Center from Ministry of Education of China and the State Administration of Foreign Experts Affairs of China(No.B18056).
Parthenolide(PTL)is a sesquiterpene lactone derived from medicinal plant feverfew(Tanacetum parthenium).Recent studies have demonstrated that it has multiple pharmacological activities,especially in the treatment of v...