PARACELLULAR

作品数：8被引量：63H指数：4
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相关期刊：《World Journal of Gastroenterology》《Acta Pharmaceutica Sinica B》更多>>
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Higher doses of ascorbic acid may have the potential to promote nutrient delivery via intestinal paracellular absorption
《World Journal of Gastroenterology》2021年第40期6750-6756,共7页Ivana Roosevelt Sequeira 
The significance of plasma ascorbic acid(AA)is underscored by its enzymatic and antioxidant properties as well as involvement in many aspects of health including the synthesis of biomolecules during acute illness,trau...
关键词：ASPIRIN Ascorbic acid Paracellular permeability Antioxidant Lactulose mannitol test 
Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs,enalaprilat and hexarelin, in rats被引量：1
《Acta Pharmaceutica Sinica B》2021年第6期1667-1675,共9页David Dahlgren Tobias Olander Markus Sjoblom Mikael Hedeland Hans Lennernas 
Transcellular permeation enhancers are known to increase the intestinal permeability of enalaprilat,a 349 Da peptide,but not hexarelin(887 Da).The primary aim of this paper was to investigate if paracellular permeabil...
关键词：Permeation enhancers Absorption-modifying excipients Oral peptide delivery Intestinal permeability Intestinal perfusion Pharmaceutical development 
Glutathione depleting drugs, antioxidants and intestinal calcium absorption被引量：7
《World Journal of Gastroenterology》2018年第44期4979-4988,共10页Luciana Moine María Rivoira Gabriela Díaz de Barboza Adriana Pérez Nori Tolosa de Talamoni 
Glutathione （GSH） is a tripeptide that constitutes one of the main intracellular reducing compounds. The normal content of GSH in the intestine is essential to optimize the intestinal Ca2＋ absorption. The use of GS...
关键词：GLUTATHIONE Transcellular and paracellular Ca^2＋pathways DL-buthionine-S R-sulfoximine Fructose rich diet MENADIONE Sodium deoxycholate Glutamine Ursodeoxycholic acid Melatonin Quercetin NARINGIN 
Oxidative stress, antioxidants and intestinal calcium absorption被引量：24
《World Journal of Gastroenterology》2017年第16期2841-2853,共13页Gabriela Diaz de Barboza Solange Guizzardi Luciana Moine Nori Tolosa de Talamoni 
Supported by Dr.Nori Tolosa de Talamoni from CONICET,No.PIP 2013-2015 and No.SECYT(UNC)2016,Argentina
The disequilibrium between the production of reactive oxygen(ROS) and nitrogen(RNS) species and their elimination by protective mechanisms leads to oxidative stress. Mitochondria are the main source of ROS as by-produ...
关键词：Transcellular and paracellular Ca2+pathways DL-buthionine-S R-sulfoximine MENADIONE Sodium deoxycholate Lithocholic acid Ursodeoxycholic acid MELATONIN 
Molecular aspects of intestinal calcium absorption被引量：25
《World Journal of Gastroenterology》2015年第23期7142-7154,共13页Gabriela Diaz de Barboza Solange Guizzardi Nori Tolosa de Talamoni 
Intestinal Ca2+ absorption is a crucial physiological process for maintaining bone mineralization and Ca2+ homeostasis. It occurs through the transcellular and paracellular pathways. The first route comprises 3steps: ...
关键词：INTESTINAL Ca2+ absorption Transcellularpathway PARACELLULAR route 1 25(OH)2D3 PTH PROLACTIN ESTROGEN LACTATION Pregnancy Aging 
Transepithelial leak in Barrett's esophagus patients: The role of proton pump inhibitors被引量：2
《World Journal of Gastroenterology》2012年第22期2793-2797,共5页Christopher Farrell Melissa Morgan Owen Tully Kevin Wolov Keith Kearney Benjamin Ngo Giancarlo Mercogliano James J Thornton Mary Carmen Valenzano James M Mullin 
Supported by Sharpe-Strumia Research Foundation of the Bryn Mawr Hospital
AIM： To determine if the observed paracellular sucrose leak in Barrett＇s esophagus patients is due to their pro- ton pump inhibitor （PPI） use. METHODS： The in vivo sucrose permeability test was administered to he...
关键词：Barrett＇s esophagus SUCROSE Tight junc-tion Paracellular  Omeprazole Proton pump inhibitor Transepithelial 
Omeprazole decreases magnesium transport across Caco-2 monolayers被引量：4
《World Journal of Gastroenterology》2011年第12期1574-1583,共10页Narongrit Thongon Nateetip Krishnamra 
Supported by The Thailand Research Fund(to Thongon N),No.MRG5380003
AIM:To elucidate the effect and underlying mechanisms of omeprazole action on Mg 2+ transport across the intestinal epithelium.METHODS:Caco-2 monolayers were cultured in various dose omeprazole-containing media for 14...
关键词：MAGNESIUM PARACELLULAR Proton pump inhibitor Transepithelial Tight junction 
Omeprazole induces gastric transmucosal permeability to the peptide bradykinin被引量：1
《World Journal of Gastroenterology》2010年第9期1097-1103,共7页Melissa Gabello Mary Carmen Valenzano E Peter Zurbach James M Mullin 
AIM:To investigate omeprazole-induced transepithelial gastric leak and its effects on the permeability of the peptides bradykinin and oxytocin.METHODS:Rat gastric corpus tissue was isolated and mounted in an Ussing ch...
关键词：PROTON pump inhibitor PARACELLULAR Drug delivery TIGHT junction Transepithelial 
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