CURCULIGOSIDE

作品数：3被引量：39H指数：2
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相关领域：医药卫生生物学更多>>
相关期刊：《Acta Pharmacologica Sinica》《Food Science and Human Wellness》《Acta Biochimica et Biophysica Sinica》更多>>
相关基金：国家自然科学基金更多>>
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Neuroprotective effects of curculigoside against Alzheimer’s disease via regulation oxidative stress mediated mitochondrial dysfunction in L-Glu-exposed HT22 cells and APP/PS1 mice被引量：1
《Food Science and Human Wellness》2023年第4期1265-1278,共14页Wenqi Wang Yidi Qu Siyu Li Jinyu Chu Hongxin Yang Lirong Teng Di Wang 
supported by the Science and Technology Develop Project in Jilin Province of China(20200201030JC);the Scientific Research Project of Education Department of Jilin Province in China(JJKH20211461KJ);Characteristic Innovation Project for Guangdong University of China(2019KTSCX221).
Curculigoside(CCG)is a phenolic glycoside compound extracted from the root of a natural plant called Curculigo orchioides Gaertn.In this study,the neuroprotective effect of CCG through oxidative stress mediated mitoch...
关键词：Alzheimer’s disease CURCULIGOSIDE Apoptosis Oxidative stress Mitochondrial dysfunction AMPK/Nrf2 signaling 
Curculigoside facilitates fear extinction and prevents depression-like behaviors in a mouse learned helplessness model through increasing hippocampal BDNF被引量：24
《Acta Pharmacologica Sinica》2019年第10期1269-1278,共10页San-juan Yang Zhu-jin Song Xun-cui Wang Zheng-rong Zhang Sheng-bing Wu Guo-qi Zhu 
This research was supported by the National Natural Science Foundation of China(81601181,81673716);the Anhui Natural Science Foundation(1808085J15)and the National Key R&D Program(2018YFC1204603).
Curculigoside(CUR)is the main active component of traditional Chinese medicine Curculigoorchioides Gaertn(Xianmao in Chinese),which exhibits a variety of pharmacological activities.In this study we investigated the ef...
关键词：depression CURCULIGOSIDE 7 8-dihydroxyflavone FEAR extinction learned HELPLESSNESS MODEL BDNF TRKB Akt-mTOR signaling pathway hippocampus 
Curculigoside isolated from Curculigo orchioides prevents hydrogen peroxide-induced dysfunction and oxidative damage in calvarial osteoblasts被引量：15
《Acta Biochimica et Biophysica Sinica》2012年第5期431-441,共11页Ying Wang Lu Zhao Yin Wang Jinlong Xu Yah Nie Yuanhui Guo Yongtao Tong Luping Qin Qiaoyan Zhang 
This study was supported by the grants from the National Natural Science Foundation of China （81073115）, and the Key Program for Basic Research of Shanghai （09JC1417600）.
Reactive oxygen species （ROS）, including H202, play a critical role in the pathophysiology of osteoporosis. Therefore, agents or antioxidants that can inhibit ROS production have a high clinical value in the treatme...
关键词：CURCULIGOSIDE Curculigo orchioides Gaertn （Amaryllidaceae） calvarial osteoblasts oxidative stress 
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