DEUBIQUITYLATION

作品数:1被引量:3H指数:1
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相关领域:医药卫生更多>>
相关期刊:《National Science Review》更多>>
相关基金:中国博士后科学基金国家自然科学基金国家重点基础研究发展计划更多>>
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Diet high in branched-chain amino acid promotes PDAC development by USP1-mediated BCAT2 stabilization被引量:3
《National Science Review》2022年第5期115-124,共10页Jin-Tao Li Kai-Yue Li Ying Su Yuan Shen Ming-Zhu Lei Fan Zhang Miao Yin Zheng-Jun Chen Wen-Yu Wen Wei-Guo Hu Dan Su Jia Qu Qun-Ying Lei 
supported by the Ministry of Science and Technology of China(2020YFA0803400/2020YFA0803402 and 2019YFA0801703);the National Natural Science Foundation of China(81790250/81790253,9195920,8187224,81872240,81802745 and 82002951);the Innovation Program of the Shanghai Municipal Education Commission(N173606);the China Postdoctoral Science Foundation(2021M690676)。
BCAT2-mediated branched-chain amino acid(BCAA)catabolism is critical for pancreatic ductal adenocarcinoma(PDAC)development,especially at an early stage.However,whether a high-BCAA diet promotes PDAC development in viv...
关键词:USP1 DEUBIQUITYLATION BCAT2 PANIN PDAC 
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