This work was supported by the grants from Natural Science Foundation of China (No. 81270106), Ministry of Science and Technology of China (No. 2012BA[05B00) and Ministry of Public Health (No. 201002008).
Background:It has been demonstrated that only 10%-20% cigarette smokers finally suffer chronic obstructive pulmonary disease (COPD).The underlying mechanism of development remains uncertain so far.Nitric oxide (NO...
Acknowledgements This work was supported by the National Basic Research Program of China (No 2010CB912102), the National Natural Science Foundation of China (No 30623003, 30740084, and 30871284), the Chinese Academy of Sciences (No 2008KIP101, KSCX1-YW-22), the Science and Technology Commission of Shanghai Municipality (No 08PJ14105, 09JC1416300) and the Hundred Talents Program of the Chinese Academy of Sciences to Prof Hong-bin JI.
Lung cancer patients with the epidermal growth factor receptor (EGFR) kinase domain mutations frequently show good responses to small molecule tyrosine kinase inhibitors, including Iressa and Tarceva, in clinical st...