CARDIOTROPHIN-1

作品数：6被引量：25H指数：2
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相关领域：医药卫生更多>>
相关作者：董战玲余江恒王冬梅吕丹王杨更多>>
相关机构：重庆医科大学中国医学科学院北京协和医学院复旦大学山西医科大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《Chinese Medical Journal》《Journal of Geriatric Cardiology》更多>>
相关基金：国家重点基础研究发展计划海南省重点科技项目海南省教育厅科研基金更多>>
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Cardiotrophin-1 promotes cardiomyocyte differentiation from mouse induced pluripotent stem cells via JAK2/STAT3/Pim-1 signaling pathway被引量：2
《Journal of Geriatric Cardiology》2015年第6期591-599,共9页Tong LIU Ran ZHANG Tao GUO Sai MA Dong HAN Xiu-Juan LI Yan JIN Miao-Miao FAN Ya-Bin WANG Yun-Dai CHEN Feng CAO 
This work was supported by the National Funds for Distinguished Young Scientists of China （No. 81325009） and National Nature Science Foundation of China （No. 81270168, No. 81227901）, （Feng Cao BWS12J037）, Innovation Team granted by Ministry of Education PRC （IRT1053）, National Basic Research Program of China （2012CB518101）. Shaanxi Province Program （2013K12-02-03, 2014KCT-20）. The authors declare no conflict of interest.
Background The induced pluripotent stem cell （iPSC） has shown great potential in cellular therapy of myocardial infarction （MI）, while its application is hampered by the low efficiency of cardiomyocyte differentia...
关键词：Cardiac differentiation CARDIOTROPHIN-1 Mouse induced pluripotent stem cells PIM-1 
CT-1-CP-induced Ventricular Electrical Remodeling in Mice
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2015年第1期21-27,共7页陈淑芬 魏桃枝 饶利亚 许闽广 董战玲 
The chronic effects of carboxyl-terminal polypeptide of Cardiotrophin-1（CT-1-CP） on ventricular electrical remodeling were investigated. CT-1-CP, which contains 16 amino acids in sequence of the C-terminal of Cardio...
关键词：carboxyl-terminal polypeptide of cardiotrophin-1 monophasic action potential action potential duration electrical remodeling 
Expression Patterns of Sarcomeric α-Actin, α-Actinin and UCP_2 in the Myocardium of Kunming Mice after Exposure to C-Terminal Polypeptide of Cardiotrophin-1被引量：1
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2014年第6期796-800,共5页陈淑芬 饶利亚 魏桃枝 许闽广 董战玲 
Cardiotrophin-1 （CT-1） activates a distinct form of cardiac muscle cell hypertrophy in which the sarcomeric units are assembled in series. The aim of the study was to determine the expres- sion pattern of sarcomeric...
关键词：carboxy-terminal polypeptide of cardiotrophin-1 sarcomaric α-actin α-actinin mitochon-drial uncoupling protein-2 
Cardiotrophin-1 induces intercellular adhesion molecule-1 expression by nuclear factor κB activation in human umbilical vein endothelial cells被引量：2
《Chinese Medical Journal》2008年第24期2592-2598,共7页Michael Fritzenwanger Martin Foerster Katharina Meusel Christian Jung Hans R. Figulla 
Background In addition to elevated concentrations of cytokines, patients with congestive endothelial dysfunction and increased plasma concentrations of adhesion molecules heart failure （CHF） show ke intercellular ad...
关键词：CARDIOTROPHIN-1 intercellular adhesion molecule-1 nuclear factor κB human umbilical vein endothelial cells 
Different contributions of STAT3, ERK1/2, and PI3-K signaling to cardiomyocyte hypertrophy by cardiotrophin-1被引量：16
《Acta Pharmacologica Sinica》2004年第9期1157-1164,共8页Ze-junTIAN WeiCUI Yong-junLI Yu-mingHAO JunDU FanLIU HuiZHANG Xiu-guangZU Su-yunLIU LiCHEN WeiAN 
ProjectsupportedbytheHebeiProvincialScientific&Tech-nologicalResearchGrants(No01276183D,00276149D,and02-025)andSpecialGrantofMunicipalKeyLaboratoryBeijing.
AIM: To assess the contribution of signal transducer and activator of transcription 3 (JAK-STAT3) pathway, extracellular signal-regulated kinases1/2 (ERK1/2) pathway, and phosphatidylinositol 3-kinase (PI3-K) pathway ...
关键词：cardiac hypertrophy signal transduction CARDIOTROPHIN-1 MAP kinase signaling system trans- activators 1-phosphatidylinosito1 3-kinase 
Crosstalk between ERK_(1/2) and STAT_3 in the modulation of cardiomyocyte hypertrophy induced by cardiotrophin-1被引量：8
《Chinese Medical Journal》2004年第8期1135-1142,共8页李拥军 崔炜 田泽君 郝玉明 都军 刘凡 张辉 祖秀光 刘素云 谢瑞琴 杨晓红 武宇洲 陈莉 安威 
ThisworkwassupportedbytheHebeiProvincialDoctoralResearchFoundation (NoB2001104)andtheBeijingSpecialGrantforMunicipalKeyLaboratories
Background The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway and the extracellular signal-regulated kinases 1/2 (ERK 1/2 ) pathway are the two major independent signal transduct...
关键词：cardiac hypertrophy CYTOKINES signal transduction 
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