supported by grants from the National Natural Science Foundation of China (32271034,32070964,81971309,32170980,and 32300791);National Key Research and Development Program of China (2021ZD0201703);Chongqing Natural Science Fund for Distinguished Young Scholars (CSTB2023NSCQ-JQX0030);Guangdong Basic and Applied Basic Research Foundation (2022B1515020012,2021A1515110268,2023A1515010651);Shenzhen Medical Research Fund (A2303014);Shenzhen Fundamental Research Program (JCYJ20210324123212035,RCYX20200714114644167,ZDSYS20220606100801003,RCBS20210706092411028,and JCYJ20210324121214039);Shenzhen Key Laboratory of Chinese Medicine Active Substance Screening and Translational Research (ZDSYS20220606100801003).
Oligodendrocyte precursor cells(OPCs)are a heterogeneous multipotent population in the central nervous system(CNS)that appear during embryogenesis and persist as resident cells in the adult brain parenchyma.OPCs could...