SPHINGOSINE

作品数：80被引量：236H指数：8
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相关作者：张翼肖琼尹大力徐美林王菁更多>>
相关机构：北京协和医学院首都医科大学天津市胸科医院天津医科大学更多>>
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相关基金：国家自然科学基金广东省自然科学基金北京市自然科学基金国家重点基础研究发展计划更多>>
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Molecular basis of Spns2-facilitated sphingosine-1-phosphate transport
《Cell Research》2024年第2期173-176,共4页Bin Pang Leiye Yu Tong Li Haizhan Jiao Xiaomei Wu Jinxin Wang Ruiping He Yurou Zhang Juan Wang Hongli Hu Wei Dai Li Chen Ruobing Ren 
Dear Editor,As one of the critical sphingolipid metabolites in eukaryotes,sphingosine-1-phosphate(S1P)acts as a bioactive lipid mediator in the immune and vascular systems.S1P prompts its physiological roles through t...
关键词：NS2 PROMPT MAINTAIN 
Structural basis of Sphingosine-1-phosphate transport via human SPNS2
《Cell Research》2024年第2期177-180,共4页Yaning Duan Nancy C.P.Leong Jing Zhao Yu Zhang Dat T.Nguyen Hoa T.T.Ha Na Wang Ruixue Xia Zhenmei Xu Zhengxiong Ma Yu Qian Han Yin Xinyan Zhu Anqi Zhang Changyou Guo Yu Xia Long N.Nguyen Yuanzheng He 
supported by the Startup Funds of HIT Center for Life Sciences;the National Natural Science Foundation of China(32070048 to Y.H.);Tsinghua University Initiative Scientific Research Program to Y.X.;We thank Dr.Zhiwei Huang of the HIT Center for Life Sciences for suggestion and support of this project,and Singapore Ministry of Health’s National ResearchOFIRG/OFIRG/0066/20;Ministry of Education MOE2018-T2-1-126,NUHSRO/2022/067/T1,and T2EP30123-0014(to L.N.N.).
Dear Editor,Sphingosine 1-phosphate(S1P)plays crucial roles in various physiological processes,including immune response,vascular development,and neural system homeostasis1 through activating S1P receptors(S1PRs).Nota...
关键词：HOMEOSTASIS TRANSPORT SINE 
Structural insights into sphingosine-1-phosphate recognition and ligand selectivity of S1PR3–Gi signaling complexes被引量：2
《Cell Research》2022年第2期218-221,共4页Chang Zhao Lin Cheng Wei Wang Heli Wang Yongbo Luo Yuying Feng Xuehui Wang Hong Fu Ye Cai Shengyong Yang Ping Fu Wei Yan Zhenhua Shao 
This work was supported by the Natural Science Foundation of China(3210110109 to W.Y.,3210110086 to L.C.,32070049 to Z.S.);Ministry of Science and Technology of China grant(2019YFA0508800 to Z.S.);Science and Technology department of Sichuan Province(2020YJ0208 to Z.S.).
Dear Editor,Lipids are essential for all life on earth and play critical roles in energy storage and the formation of cellular membranes.Sphingosine-1-phosphate(S1P)is a naturally occurring bioactive lysophospholipid ...
关键词：COMPLEXES SELECTIVITY INSIGHT 
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