supported by the National Natural Science Foundation of China(31210103916;91329302 and 91519330);the Progress on CAS Strategic Priority Research Program(XDA01010303);the Instrument Developing Project of the Chinese Academy of Sciences(YZ201243);the National Basic Research Program of China(2015CB964803 and 2011CB504206)to Jing-Dong J.Han
Super-enhancers are defined as cluster of enhancers with dense TF binding, which can activate proximal cell-identity gene expression. Here we review the identification, func- tional significance of super-enhancers, an...