funded by the National ScienceFoundation of China(81271468,81130020,81171267);the Pillar Projects of the Twelfth 5-year Plan of China(2012BAI01B07);the New 100-People Plan of the health system in the city of Shanghai,the National Key Specialized Clinical Medicine-Shanghai Mental Health Center(Medical Administrative Department of the Ministry of Health,2011-873);the Shanghai Health Bureau Foundation(2011Y097)